{"title":"基质相互作用调节上皮极性和内聚在第二心脏区","authors":"Robert G. Kelly","doi":"10.1016/j.devcel.2024.12.017","DOIUrl":null,"url":null,"abstract":"Addition of epithelial progenitor cells drives progressive extension of the heart tube during cardiac morphogenesis. In this issue of <em>Developmental Cell,</em> Arriagada et al. (2024) refine our understanding of how these cells condition and interact with the underlying extracellular matrix, demonstrating that autonomous fibronectin synthesis controls their apicobasal polarity and deployment to the heart.","PeriodicalId":11157,"journal":{"name":"Developmental cell","volume":"34 1","pages":""},"PeriodicalIF":10.7000,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Matrix interactions regulate epithelial polarity and cohesion in the second heart field\",\"authors\":\"Robert G. Kelly\",\"doi\":\"10.1016/j.devcel.2024.12.017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Addition of epithelial progenitor cells drives progressive extension of the heart tube during cardiac morphogenesis. In this issue of <em>Developmental Cell,</em> Arriagada et al. (2024) refine our understanding of how these cells condition and interact with the underlying extracellular matrix, demonstrating that autonomous fibronectin synthesis controls their apicobasal polarity and deployment to the heart.\",\"PeriodicalId\":11157,\"journal\":{\"name\":\"Developmental cell\",\"volume\":\"34 1\",\"pages\":\"\"},\"PeriodicalIF\":10.7000,\"publicationDate\":\"2025-01-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Developmental cell\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.devcel.2024.12.017\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Developmental cell","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.devcel.2024.12.017","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
Matrix interactions regulate epithelial polarity and cohesion in the second heart field
Addition of epithelial progenitor cells drives progressive extension of the heart tube during cardiac morphogenesis. In this issue of Developmental Cell, Arriagada et al. (2024) refine our understanding of how these cells condition and interact with the underlying extracellular matrix, demonstrating that autonomous fibronectin synthesis controls their apicobasal polarity and deployment to the heart.
期刊介绍：
Developmental Cell, established in 2001, is a comprehensive journal that explores a wide range of topics in cell and developmental biology. Our publication encompasses work across various disciplines within biology, with a particular emphasis on investigating the intersections between cell biology, developmental biology, and other related fields. Our primary objective is to present research conducted through a cell biological perspective, addressing the essential mechanisms governing cell function, cellular interactions, and responses to the environment. Moreover, we focus on understanding the collective behavior of cells, culminating in the formation of tissues, organs, and whole organisms, while also investigating the consequences of any malfunctions in these intricate processes.
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