中国独居老年人抑郁和焦虑症状的网络分析——基于2017-2018年中国健康长寿纵向调查(CLHLS)

IF 3.4 2区 医学 Q2 PSYCHIATRY BMC Psychiatry Pub Date : 2025-01-08 DOI:10.1186/s12888-024-06443-2
Ze Chang, Yunfan Zhang, Xiao Liang, Yunmeng Chen, Chunyan Guo, Xiansu Chi, Liuding Wang, Xie Wang, Hong Chen, Zixuan Zhang, Longtao Liu, Lina Miao, Yunling Zhang
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引用次数: 0

摘要

背景:独居老人是家庭支持有限的弱势群体,使他们更容易受到抑郁和焦虑等心理健康问题的影响。本研究旨在构建独居老年人抑郁和焦虑症状的网络模型,探讨不同症状的相关性和中心性。目标是确定核心和过渡性症状,为临床干预提供信息。方法:利用2018年中国纵向健康寿命调查(CLHLS)数据,构建独居老年人抑郁和焦虑症状的网络模型。抑郁和焦虑症状分别使用流行病学研究中心抑郁量表-10 (csd -10)和广泛性焦虑障碍量表-7 (GAD-7)进行评估。采用高斯图形模型(Gaussian Graphical Model, GGM)构建症状网络,采用Fruchterman-Reingold算法进行可视化,边缘的厚度和颜色表示症状之间的部分相关性。采用最小绝对收缩和选择算子(LASSO)方法进行正则化,利用扩展贝叶斯信息准则(EBIC)选择最优正则化参数。我们进一步计算预期影响(EI)和桥预期影响(Bridge EI)来评估症状的重要性。采用非参数自举法评估网络的稳定性和准确性。结果:网络中心性分析显示,GAD2(无法控制的担忧)和GAD4(麻烦放松)的强度中心性最高(分别为1.128和1.102),表明它们与其他症状有显著的直接关联,是焦虑症状网络的核心节点。其他高度中枢的节点,如GAD1(紧张或焦虑)和GAD3(广泛性担忧),进一步强调了焦虑症状在整个网络中的主导地位。间性中心性结果强调GAD1(紧张或焦虑)和GAD2(无法控制的担忧)是促进不同症状之间信息流动的关键桥梁节点,而CESD3(感觉抑郁)在各个模块之间表现出桥梁作用。加权分析进一步证实了GAD2(无法控制的担忧)和GAD4(麻烦放松)的中心重要性。此外,分析还显示了独居老年人抑郁-焦虑网络的性别差异。结论:本研究通过网络分析揭示了独居老年人抑郁与焦虑症状之间的复杂关系,确定了GAD2 (controlled worry)和GAD4 (Trouble relaxation)为核心症状。这些发现为有针对性的干预措施提供了重要的见解。未来的研究应探索对这些症状的干预策略,以改善独居老年人的心理健康。
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A network analysis of depression and anxiety symptoms among Chinese elderly living alone: based on the 2017-2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS).

Background: Elderly individuals living alone represent a vulnerable group with limited family support, making them more susceptible to mental health issues such as depression and anxiety. This study aims to construct a network model of depression and anxiety symptoms among older adults living alone, exploring the correlations and centrality of different symptoms. The goal is to identify core and bridging symptoms to inform clinical interventions.

Methods: Using data from the 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS), this study constructed a network model of depression and anxiety symptoms among elderly individuals living alone. Depression and anxiety symptoms were assessed using the Center for Epidemiologic Studies Depression Scale-10 (CESD-10) and the Generalized Anxiety Disorder Scale-7 (GAD-7), respectively. A Gaussian Graphical Model (GGM) was employed to build the symptom network, and the Fruchterman-Reingold algorithm was used for visualization, with the thickness and color of the edges representing partial correlations between symptoms. To minimize spurious correlations, the Least Absolute Shrinkage and Selection Operator (LASSO) method was applied for regularization, and the optimal regularization parameters were selected using the Extended Bayesian Information Criterion (EBIC). We further calculated Expected Influence (EI) and Bridge Expected Influence (Bridge EI) to evaluate the importance of symptoms. Non-parametric bootstrap methods were used to assess the stability and accuracy of the network.

Results: The Network centrality analysis revealed that GAD2 (Uncontrollable worry) and GAD4 (Trouble relaxing) exhibited the highest strength centrality (1.128 and 1.102, respectively), indicating their significant direct associations with other symptoms and their roles as core nodes in the anxiety symptom network. Other highly central nodes, such as GAD1 (Nervousness or anxiety) and GAD3 (Generalized worry), further underscore the dominance of anxiety symptoms in the overall network. Betweenness centrality results highlighted GAD1 (Nervousness or anxiety) and GAD2 (Uncontrollable worry) as critical bridge nodes facilitating information flow between different symptoms, while CESD3 (Feeling depressed) demonstrated a bridging role across modules. Weighted analyses further confirmed the central importance of GAD2 (Uncontrollable worry) and GAD4 (Trouble relaxing). Additionally, the analysis showed gender differences in the depression-anxiety networks of elderly individuals living alone.

Conclusion: This study, through network analysis, uncovered the complex relationships between depression and anxiety symptoms among elderly individuals living alone, identifying GAD2 (Uncontrollable worry) and GAD4 (Trouble relaxing) as core symptoms. These findings provide essential insights for targeted interventions. Future research should explore intervention strategies for these symptoms to improve the mental health of elderly individuals living alone.

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来源期刊
BMC Psychiatry
BMC Psychiatry 医学-精神病学
CiteScore
5.90
自引率
4.50%
发文量
716
审稿时长
3-6 weeks
期刊介绍: BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
期刊最新文献
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