通过多导睡眠图诊断的儿童和青少年阻塞性睡眠呼吸暂停相关因素:范围综述。

IF 3.5 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Respiratory medicine Pub Date : 2025-02-01 DOI:10.1016/j.rmed.2025.107942
Júlia M. Saporiti DDS, MSc, PhD student, Thiago A. de Holanda DDS, MSc, PhD, Gabriela G. Torino DDS, MSc, PhD student, Noéli Boscato DDS, MSc, PhD
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引用次数: 0

摘要

目的:本综述旨在通过夜间多导睡眠图(PSG)和基于问卷的诊断评估,绘制儿童和青少年阻塞性睡眠呼吸暂停(OSA)相关因素的研究图谱。方法:截至2023年5月,在三个电子数据库中进行检索,包括9项观察性研究,包括3482名个体。结果:在纳入的研究中,9项涉及性,6项涉及肥胖,5项涉及扁桃体肥大,3项涉及口呼吸,2项涉及过敏性鼻炎,3项涉及吸烟。样本包括3482名儿童,并对性别(n = 3482)、肥胖(n = 2752)和扁桃体肥大(n = 794)进行了分析。meta分析显示,男性的OSA患病率明显高于女性[P 2 = 49%],合并相对危险度(RR)为1.15(95%可信区间[CI]: 1.07-1.23)。肥胖与阻塞性睡眠呼吸暂停存在关联[RR: 1.42;95% ci: 1.20-1.68;p = 0.02;[2 = 61%],扁桃体大小与OSA [RR: 1.61;95% ci: 1.35-1.92;p = 0.06;i2 = 60%]。结论:考虑到研究的局限性,这些发现强调了在评估儿童和青少年OSA时考虑性别、肥胖和扁桃体大小的重要性。
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Obstructive sleep apnoea-associated factors in children and adolescents diagnosed by polysomnography: A scoping review

Purpose

This scoping review aimed to map research on factors associated with obstructive sleep apnoea (OSA) in children and adolescents undergoing overnight polysomnography (PSG) and questionnaire-based diagnostic assessments.

Methods

Searches were conducted in three electronic databases up to May 2023, including nine observational studies, including 3482 individuals.

Results

Among the included studies, nine reported on sex, six on obesity, five on tonsillar hypertrophy, three on mouth breathing, two on allergic rhinitis, and three on smoking exposure. The sample comprised 3482 children, with subsets analyzed for sex (n = 3482), obesity (n = 2752), and tonsillar hypertrophy (n = 794). Meta-analysis demonstrated a significantly higher prevalence of OSA in males compared to females [P < 0.0001; I2 = 49 %], with a pooled relative risk (RR) of 1.15 (95 % confidence interval [CI]: 1.07–1.23). Associations were found between obesity and OSA [RR: 1.42; 95 % CI: 1.20–1.68; P = 0.02; I2 = 61 %], and tonsillar size and OSA [RR: 1.61; 95 % CI: 1.35–1.92; P = 0.06; I2 = 60 %].

Conclusion

Considering the study's limitations, these findings underscore the importance of considering sex, obesity, and tonsillar size when evaluating OSA in children and adolescents.
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来源期刊
Respiratory medicine
Respiratory medicine 医学-呼吸系统
CiteScore
7.50
自引率
0.00%
发文量
199
审稿时长
38 days
期刊介绍: Respiratory Medicine is an internationally-renowned journal devoted to the rapid publication of clinically-relevant respiratory medicine research. It combines cutting-edge original research with state-of-the-art reviews dealing with all aspects of respiratory diseases and therapeutic interventions. Topics include adult and paediatric medicine, epidemiology, immunology and cell biology, physiology, occupational disorders, and the role of allergens and pollutants. Respiratory Medicine is increasingly the journal of choice for publication of phased trial work, commenting on effectiveness, dosage and methods of action.
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