外泌体在医学皮肤病学中的作用:文献回顾与更新。

IF 2.3 4区 医学 Q2 DERMATOLOGY Journal of Cosmetic Dermatology Pub Date : 2025-01-10 DOI:10.1111/jocd.16761
Victoria Dukharan, Milaan Shah, Luke Broughton, Carol Stegura, Luna Samman, Nina Schur, Todd Schlesinger
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引用次数: 0

摘要

背景:外泌体是细胞外囊泡,由磷脂双分子层组成,主要来源于干细胞。外泌体的内容物可以被纳入它们被引入的组织中,这提供了一种独特的治疗选择。目的:外泌体作为一种治疗多种疾病的药物已被研究,但文献支持这些适应症尚无定论。此外,关于外泌体及其用途的许多研究最近才完成。因此,本文综述了外泌体治疗不同皮肤病的疗效和意义。方法:对外泌体治疗多种皮肤病的相关文献进行综述。此外,我们提出了许多实际病例,其中患者已与外泌体治疗。结果:总体而言,外泌体在治疗医学皮肤病方面的成功在文献中表现出不同的疗效,但初步证据通常是积极的。患者病例也显示出令人满意的临床结果,但需要进一步的研究和病例来充分表征外泌体的疗效及其应用的理想方式,包括配方、分布模式和治疗频率。结论:外泌体可作为创面愈合、皮瓣重建、放射性皮炎、寻常性痤疮、银屑病、特应性皮炎、过敏性接触性皮炎、慢性单纯性地衣、外唇地衣硬化、系统性硬化症、系统性红斑狼疮和白癜风的有效治疗选择,但其有效性和安全性有待进一步研究证实。
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The Role of Exosomes in Medical Dermatology: Literature Review and Update

January 30, 2025: This article published prematurely in error. The article will republish shortly.

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来源期刊
CiteScore
4.30
自引率
13.00%
发文量
818
审稿时长
>12 weeks
期刊介绍: The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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