{"title":"IGFBP6有助于血管恢复。","authors":"Martin A. Schwartz","doi":"10.1038/s44161-024-00597-8","DOIUrl":null,"url":null,"abstract":"Atherosclerosis and other vascular inflammatory diseases are determined by the balance between pro- and anti-inflammatory pathways. A report now identifies IGFBP6 as a component of an anti-inflammatory, protective program in vascular endothelial cells and demonstrates that major vault protein is the key downstream effector.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"4 2","pages":"122-123"},"PeriodicalIF":9.4000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"IGFBP6 contributes to vascular resilience\",\"authors\":\"Martin A. Schwartz\",\"doi\":\"10.1038/s44161-024-00597-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Atherosclerosis and other vascular inflammatory diseases are determined by the balance between pro- and anti-inflammatory pathways. A report now identifies IGFBP6 as a component of an anti-inflammatory, protective program in vascular endothelial cells and demonstrates that major vault protein is the key downstream effector.\",\"PeriodicalId\":74245,\"journal\":{\"name\":\"Nature cardiovascular research\",\"volume\":\"4 2\",\"pages\":\"122-123\"},\"PeriodicalIF\":9.4000,\"publicationDate\":\"2025-01-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature cardiovascular research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44161-024-00597-8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-024-00597-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Atherosclerosis and other vascular inflammatory diseases are determined by the balance between pro- and anti-inflammatory pathways. A report now identifies IGFBP6 as a component of an anti-inflammatory, protective program in vascular endothelial cells and demonstrates that major vault protein is the key downstream effector.