INSPIRE的设计:评估在实施筛查、简短干预、转诊治疗和初级保健中不健康酒精使用的药物治疗方面的实践促进的有效性。

IF 1.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Contemporary Clinical Trials Communications Pub Date : 2025-02-01 DOI:10.1016/j.conctc.2024.101413
Jennifer Bannon , Justin D. Smith , Mark J. Van Ryzin , Megan McHugh , Jennifer Heinrich , Theresa L. Walunas , Abel N. Kho
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引用次数: 0

摘要

背景:不健康饮酒是可预防死亡的主要原因,也是一系列社会和健康问题的危险因素。对小型初级保健实践进行干预以实施减少不健康酒精使用(INSPIRE)研究是一项全国运动的一部分,目的是改进对不健康酒精使用患者的识别和治疗。方法:我们进行了一项单组实用研究,包括芝加哥大都会区、威斯康辛州和加利福尼亚州的17家初级保健诊所,分为两波,潜伏期为6个月,干预期为12个月,持续期为6个月。登记的诊所是独立的、联邦认证的健康中心、基于网络的和学术的健康中心。INSPIRE利用RE-AIM(覆盖范围、有效性、采用、实施、维持)框架来检查临床医生在初级保健诊所实践中采用筛查、短暂干预、转诊治疗(SBIRT)和不健康酒精使用药物(MAUD)活动的实施可行性、保真度和表现。结果:从2020年3月到2021年12月,在21个月的时间里,17个符合条件的初级保健实践被纳入研究。由于2019冠状病毒病大流行,从2020年3月到2020年7月,招聘暂停。大多数登记的诊所都是小型诊所(结论:INSPIRE研究将评估小型诊所的初级保健临床医生参与实践教育计划和实施标准筛查和治疗方案的能力,这些方案适用于电子健康记录(EHR)的记录。该研究还将利用定量和定性分析方法查明促进或阻碍改进和可持续性的因素。
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Design of INSPIRE: Evaluation of the effectiveness of practice facilitation on implementation of screening, brief interventions, referral to treatment and medication for unhealthy alcohol use identification and treatment in primary care

Background

Unhealthy alcohol use is a leading cause of preventable mortality and a risk factor for an array of social and health problems. The Intervention in Small primary care Practices to Implement Reduction in unhealthy alcohol use (INSPIRE) study is part of a nationwide campaign to improve the identification and treatment of patients engaging in unhealthy alcohol use.

Methods

We conducted a single arm, pragmatic study consisting of seventeen primary care practices in the Chicago metropolitan area, Wisconsin, and California across two waves with a 6-month latent period, a 12-month intervention period, followed by a 6-month sustainability period. Enrolled practices were independent, Federally Qualified Health Centers, network-based, and academic health centers. INSPIRE utilized the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) framework to examine implementation feasibility, fidelity, and performance of clinicians on practice adoption of screening, brief intervention, referral to treatment (SBIRT) and medication for unhealthy alcohol use (MAUD) activities in primary care clinics.

Results

Seventeen eligible primary care practices were enrolled over the course of 21 months beginning in March of 2020 through December of 2021. There was a pause in recruitment from March of 2020 through July of 2020 due to the Covid-19 pandemic. The majority of enrolled practices were small (<6 clinicians) and were part of a network. 57 % of clinicians completed the educational modules in part or in full.
This paper will outline the INSPIRE protocol and design. Additionally, we will present practice demographic data, recruitment data and results related to on-line learning module completion.

Conclusion

The INSPIRE study will evaluate the ability of primary care clinicians in small practices to participate in practice education programs and implement standard screening and treatment protocols, adapted for documentation in the electronic health record (EHR). The study will also identify the factors that facilitated or hindered improvement and sustainability using quantitative and qualitative analysis methods.
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来源期刊
Contemporary Clinical Trials Communications
Contemporary Clinical Trials Communications Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
2.70
自引率
6.70%
发文量
146
审稿时长
20 weeks
期刊介绍: Contemporary Clinical Trials Communications is an international peer reviewed open access journal that publishes articles pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from a wide range of disciplines including medicine, life science, pharmaceutical science, biostatistics, epidemiology, computer science, management science, behavioral science, and bioethics. Contemporary Clinical Trials Communications is unique in that it is outside the confines of disease specifications, and it strives to increase the transparency of medical research and reduce publication bias by publishing scientifically valid original research findings irrespective of their perceived importance, significance or impact. Both randomized and non-randomized trials are within the scope of the Journal. Some common topics include trial design rationale and methods, operational methodologies and challenges, and positive and negative trial results. In addition to original research, the Journal also welcomes other types of communications including, but are not limited to, methodology reviews, perspectives and discussions. Through timely dissemination of advances in clinical trials, the goal of Contemporary Clinical Trials Communications is to serve as a platform to enhance the communication and collaboration within the global clinical trials community that ultimately advances this field of research for the benefit of patients.
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