2017年至2019年纽约57个县阿片类药物使用障碍患病率:贝叶斯证据综合

IF 3.9 2区 医学 Q1 PSYCHIATRY Drug and alcohol dependence Pub Date : 2025-02-01 DOI:10.1016/j.drugalcdep.2025.112548
Tian Zheng , Katherine Keyes , Shouxuan Ji , Anna Calderon , Elwin Wu , Nathan J. Doogan , Jennifer Villani , Redonna Chandler , Joshua A. Barocas , Trang Nguyen , Nabila El-Bassel , Daniel J. Feaster
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引用次数: 0

摘要

导言:地方一级阿片类药物使用障碍(OUD)的患病率估计对公共卫生规划和监测至关重要,但在美国各地,特别是在地方县级,基本上无法获得。方法:我们使用贝叶斯证据综合方法估计2017-2019年纽约州57个县的OUD患病率,比较各县的OUD发病率,并评估未确诊OUD的程度。我们开发了一个生成模型来评估由诊断、治疗和过量致死定义的OUD人群不同亚组之间的条件概率关系。结果:2017 - 2019年平均OUD患病率为2.4%(威彻斯特县)至8.3%(沙利文县)。总体OUD患病率估计每年相对稳定,从2018年的4.5%到2017年和2019年的4.6%。按年龄和性别划分,贝叶斯证据综合估计始终高于医疗补助中诊断出的百分比。到2019年,未确诊的OUD的估计比例从克林顿县的16.7%到奥农达加县的62.7%不等。过量死亡率相对较高和丁丙诺啡处方百分比较低的县,未确诊OUD的估计水平最高。结论:不同州的OUD患病率差异很大。我们确定了OUD和过量水平高的县,以及未确诊的OUD比例高的县,从而深入了解需要快速扩大OUD患者服务的州。贝叶斯证据综合方法是一种可靠而严格的方法,可以为局部地区提供有关OUD大小的信息。
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Opioid use disorder prevalence in 57 New York counties from 2017 to 2019: A Bayesian evidence synthesis

Introduction

Prevalence estimates of opioid use disorder (OUD) at local levels are critical for public health planning and surveillance, yet largely unavailable across the US especially at the local county level.

Methods

We used a Bayesian evidence synthesis approach to estimate the prevalence of OUD for 57 counties across New York State for 2017–2019 and compare rates of OUD across counties as well as assess the extent of undiagnosed OUD. We developed a generative model to assess conditional probabilistic relations between different subgroups of the OUD population defined by diagnosis, treatment, and overdose fatality.

Results

Average OUD prevalence from 2017 to 2019 ranged from 2.4 % (Westchester County) to 8.3 % (Sullivan County). Overall OUD prevalence estimates were relatively stable year to year, from 4.5 % in 2018 and 4.6 % in both 2017 and 2019. The Bayesian evidence synthesis estimate is consistently higher than the percentage diagnosed in Medicaid, by age and sex. By 2019, the estimated proportion of OUD that was undiagnosed ranged from 16.7 % in Clinton County to 62.7 % in Onondaga County. Counties with relatively high overdose death rates and low buprenorphine prescription percentages had the highest estimated level of undiagnosed OUD.

Conclusion

OUD prevalence varied considerably across the state. We identified counties with high OUD and overdose levels and a high proportion of undiagnosed OUD, providing insight into areas of the state in need of rapid expansion of services for people with OUD. Bayesian evidence synthesis approaches for OUD prevalence estimation represent a reliable and rigorous approach to providing local areas with information on OUD magnitude.
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来源期刊
Drug and alcohol dependence
Drug and alcohol dependence 医学-精神病学
CiteScore
7.40
自引率
7.10%
发文量
409
审稿时长
41 days
期刊介绍: Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.
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