肿瘤边界的动态聚焦:用于MRI脑肿瘤分割的轻量级U-Net。

IF 3.7 3区 医学 Q2 ENGINEERING, BIOMEDICAL Bioengineering Pub Date : 2024-12-23 DOI:10.3390/bioengineering11121302
Kuldashboy Avazov, Sanjar Mirzakhalilov, Sabina Umirzakova, Akmalbek Abdusalomov, Young Im Cho
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引用次数: 0

摘要

在MRI扫描中准确分割脑肿瘤对诊断和治疗计划至关重要。传统的分割模型,如U-Net,擅长捕获空间信息,但往往难以处理复杂的肿瘤边界和图像对比度的微妙变化。这些限制可能导致识别关键区域的不一致,影响临床结果的准确性。为了解决这些挑战,本文提出了一种对U-Net架构的新颖修改,通过集成空间注意机制,旨在动态关注MRI扫描中的相关区域。这一创新增强了模型描绘精细肿瘤边界的能力,提高了分割精度。我们的模型在Figshare数据集上进行了评估,该数据集包括脑膜瘤、胶质瘤和垂体瘤的注释MRI图像。该模型的Dice相似系数(DSC)为0.93,召回率为0.95,AUC为0.94,优于现有的V-Net、DeepLab V3+和nnU-Net方法。这些结果证明了我们的模型在解决低对比度边界、小肿瘤区域和重叠肿瘤等关键挑战方面的有效性。此外,该模型的轻量化设计确保其适合实时临床应用,使其成为自动肿瘤分割的强大工具。这项研究强调了空间注意机制在显著增强医学成像模型方面的潜力,并为更有效的诊断工具铺平了道路。
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Dynamic Focus on Tumor Boundaries: A Lightweight U-Net for MRI Brain Tumor Segmentation.

Accurate segmentation of brain tumors in MRI scans is critical for diagnosis and treatment planning. Traditional segmentation models, such as U-Net, excel in capturing spatial information but often struggle with complex tumor boundaries and subtle variations in image contrast. These limitations can lead to inconsistencies in identifying critical regions, impacting the accuracy of clinical outcomes. To address these challenges, this paper proposes a novel modification to the U-Net architecture by integrating a spatial attention mechanism designed to dynamically focus on relevant regions within MRI scans. This innovation enhances the model's ability to delineate fine tumor boundaries and improves segmentation precision. Our model was evaluated on the Figshare dataset, which includes annotated MRI images of meningioma, glioma, and pituitary tumors. The proposed model achieved a Dice similarity coefficient (DSC) of 0.93, a recall of 0.95, and an AUC of 0.94, outperforming existing approaches such as V-Net, DeepLab V3+, and nnU-Net. These results demonstrate the effectiveness of our model in addressing key challenges like low-contrast boundaries, small tumor regions, and overlapping tumors. Furthermore, the lightweight design of the model ensures its suitability for real-time clinical applications, making it a robust tool for automated tumor segmentation. This study underscores the potential of spatial attention mechanisms to significantly enhance medical imaging models and paves the way for more effective diagnostic tools.

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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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