Mohammad Vaziri, Maryam Abedini Baghbadorani, Monireh Khandaee Ghamsari, Somayeh Handali
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The prospect of using nanotechnology to prevent and treat infections caused by Listeria monocytogenes.
Listeria monocytogenes (L. monocytogenes) is an opportunistic intracellular pathogen that causes listeriosis in human and leads to high mortality rate. L. monocytogenes is resistant to various antibiotics due to its ability to form biofilm. Designing a new generation of antibiotics is a very expensive and time-consuming process. Moreover, the protection of antibiotics via drug delivery system can promote their effectiveness and bioavailability. Nanomedicine can be a promising tool for treating intracellular bacteria and preventing the recurrence of infections. Nanocarriers can be employed as antibacterial agents or as a carrier for antibacterial agents. In the present review, the application of nanotechnology has been discussed for the prevention and treatment of Listeria infection. According to the studies, the application of nanomaterials can be a potential strategy to eradicate infections caused by L. monocytogenes.
期刊介绍:
Critical Reviews in Microbiology is an international, peer-reviewed journal that publishes comprehensive reviews covering all areas of microbiology relevant to humans and animals, including medical and veterinary microbiology, public health and environmental microbiology. These may include subjects related to microbial molecular biology, immunopathogenicity, physiology, biochemistry, structure, and epidemiology. Of particular interest are reviews covering clinical aspects of bacterial, virological, fungal and parasitic diseases. All reviews must be analytical, comprehensive, and balanced in nature. Editors welcome uninvited submissions, as well as suggested topics for reviews accompanied by an abstract.