利用纳米技术预防和治疗单核增生李斯特菌引起的感染的前景。

IF 6 2区 生物学 Q1 MICROBIOLOGY Critical Reviews in Microbiology Pub Date : 2025-01-15 DOI:10.1080/1040841X.2025.2452571
Mohammad Vaziri, Maryam Abedini Baghbadorani, Monireh Khandaee Ghamsari, Somayeh Handali
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引用次数: 0

摘要

单核增生李斯特菌(李斯特菌)是引起人类李斯特菌病的机会性细胞内病原体,死亡率高。单核增生乳杆菌由于其形成生物膜的能力而对多种抗生素具有耐药性。设计新一代抗生素是一个非常昂贵和耗时的过程。此外,通过给药系统保护抗生素可以提高其有效性和生物利用度。纳米医学是治疗细胞内细菌和预防感染复发的一种很有前途的工具。纳米载体可以用作抗菌剂或作为抗菌剂的载体。本文就纳米技术在李斯特菌感染防治中的应用进行了综述。根据这些研究,纳米材料的应用可能是根除单核增生乳杆菌感染的潜在策略。
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The prospect of using nanotechnology to prevent and treat infections caused by Listeria monocytogenes.

Listeria monocytogenes (L. monocytogenes) is an opportunistic intracellular pathogen that causes listeriosis in human and leads to high mortality rate. L. monocytogenes is resistant to various antibiotics due to its ability to form biofilm. Designing a new generation of antibiotics is a very expensive and time-consuming process. Moreover, the protection of antibiotics via drug delivery system can promote their effectiveness and bioavailability. Nanomedicine can be a promising tool for treating intracellular bacteria and preventing the recurrence of infections. Nanocarriers can be employed as antibacterial agents or as a carrier for antibacterial agents. In the present review, the application of nanotechnology has been discussed for the prevention and treatment of Listeria infection. According to the studies, the application of nanomaterials can be a potential strategy to eradicate infections caused by L. monocytogenes.

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来源期刊
Critical Reviews in Microbiology
Critical Reviews in Microbiology 生物-微生物学
CiteScore
14.70
自引率
0.00%
发文量
99
期刊介绍: Critical Reviews in Microbiology is an international, peer-reviewed journal that publishes comprehensive reviews covering all areas of microbiology relevant to humans and animals, including medical and veterinary microbiology, public health and environmental microbiology. These may include subjects related to microbial molecular biology, immunopathogenicity, physiology, biochemistry, structure, and epidemiology. Of particular interest are reviews covering clinical aspects of bacterial, virological, fungal and parasitic diseases. All reviews must be analytical, comprehensive, and balanced in nature. Editors welcome uninvited submissions, as well as suggested topics for reviews accompanied by an abstract.
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