Mikkel Thunestvedt Hansen, Karina Husted, Johanne Louise Modvig, Kristine Kjær Lange, Cecilie Moe Weinreich, Cathrine Tranberg, Tue Rømer, Arthur Ingersen, Flemming Dela, Jørn Wulff Helge
{"title":"超重和肥胖人群在14周生活方式干预前后的V²o峰值估计。","authors":"Mikkel Thunestvedt Hansen, Karina Husted, Johanne Louise Modvig, Kristine Kjær Lange, Cecilie Moe Weinreich, Cathrine Tranberg, Tue Rømer, Arthur Ingersen, Flemming Dela, Jørn Wulff Helge","doi":"10.1038/s41366-025-01713-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the validity and applicability of a non-exercise estimation of cardiorespiratory fitness using resting seismocardiography (SCG eV̇O<sub>2</sub>peak) in people with overweight and obesity before and after a 14-week lifestyle intervention.</p><p><strong>Methods: </strong>The study was carried out at a Folk high school that offers 14-week courses on lifestyle changes where participants live at the school and voluntarily participate in daily lectures and activities. Sixty-seven men and women with age and body mass index between 18 and 70 years and 25-50 kg·m<sup>-2</sup> were tested at baseline, and 52 had a follow-up test after 14 weeks. Testing included the determination of anthropometric variables, an SCG eV̇O<sub>2</sub>peak at supine rest, and a gold standard V̇O<sub>2</sub>peak test on a cycle ergometer until voluntary exhaustion.</p><p><strong>Results: </strong>Agreement analysis for V̇O<sub>2</sub>peak at baseline (n = 67, SCG eV̇O<sub>2</sub>peak: 26.9 ± 1.9 ml·min<sup>-1</sup>·kg<sup>-1</sup>, V̇O<sub>2</sub>peak: 26.6 ± 1.6 ml·min<sup>-1</sup>·kg<sup>-1</sup>, mean ± 95% confidence interval) showed a bias of 0.3 ± 1.0 ml·min<sup>-1</sup>·kg<sup>-1</sup> with 95% limits of agreement (LoA) ranging ± 9.8 ml·min<sup>-1</sup>·kg<sup>-1</sup>. A Pearson's correlation of r = 0.78 (p < 0.0001) and a standard error of estimate (SEE) of 5.0 ml·min<sup>-1</sup>·kg<sup>-1</sup> were found between methods. At follow-up (n = 52), body mass was reduced by 6.6 ± 1.4 kg (p < 0.0001). V̇O<sub>2</sub>peak increased by 3.3 ± 0.9 ml·min<sup>-1</sup>·kg<sup>-1</sup> and 175 ± 78 ml·min<sup>-1</sup> and SCG eV̇O<sub>2</sub>peak by 2.6 ± 0.8 ml·min<sup>-1</sup>·kg<sup>-1</sup> and 93 ± 76 ml·min<sup>-1</sup> (two-way ANOVA repeated measure: intervention p < 0.0001, method p = 0.939 and interaction p = 0.125, relative V̇O<sub>2</sub>peak). A Pearson's correlation of r = 0.37 (p < 0.05) was found between changes in relative V̇O<sub>2</sub>peak but not for absolute V̇O<sub>2</sub>peak r = 0.10 (p = 0.402).</p><p><strong>Conclusions: </strong>The SCG method is accurate for estimating V̇O<sub>2</sub>peak and appropriate for detecting group changes in both relative and absolute V̇O<sub>2</sub>peak following a lifestyle intervention in people with overweight and obesity. Furthermore, the method can detect individual changes in V̇O<sub>2</sub>peak but not independently of body mass changes. Yet, the applicability is still limited by the relatively large variation in LoA and SEE.</p>","PeriodicalId":14183,"journal":{"name":"International Journal of Obesity","volume":" ","pages":""},"PeriodicalIF":4.2000,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"V̇O<sub>2</sub>peak estimation in people with overweight and obesity before and after a 14-week lifestyle intervention.\",\"authors\":\"Mikkel Thunestvedt Hansen, Karina Husted, Johanne Louise Modvig, Kristine Kjær Lange, Cecilie Moe Weinreich, Cathrine Tranberg, Tue Rømer, Arthur Ingersen, Flemming Dela, Jørn Wulff Helge\",\"doi\":\"10.1038/s41366-025-01713-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aimed to investigate the validity and applicability of a non-exercise estimation of cardiorespiratory fitness using resting seismocardiography (SCG eV̇O<sub>2</sub>peak) in people with overweight and obesity before and after a 14-week lifestyle intervention.</p><p><strong>Methods: </strong>The study was carried out at a Folk high school that offers 14-week courses on lifestyle changes where participants live at the school and voluntarily participate in daily lectures and activities. Sixty-seven men and women with age and body mass index between 18 and 70 years and 25-50 kg·m<sup>-2</sup> were tested at baseline, and 52 had a follow-up test after 14 weeks. Testing included the determination of anthropometric variables, an SCG eV̇O<sub>2</sub>peak at supine rest, and a gold standard V̇O<sub>2</sub>peak test on a cycle ergometer until voluntary exhaustion.</p><p><strong>Results: </strong>Agreement analysis for V̇O<sub>2</sub>peak at baseline (n = 67, SCG eV̇O<sub>2</sub>peak: 26.9 ± 1.9 ml·min<sup>-1</sup>·kg<sup>-1</sup>, V̇O<sub>2</sub>peak: 26.6 ± 1.6 ml·min<sup>-1</sup>·kg<sup>-1</sup>, mean ± 95% confidence interval) showed a bias of 0.3 ± 1.0 ml·min<sup>-1</sup>·kg<sup>-1</sup> with 95% limits of agreement (LoA) ranging ± 9.8 ml·min<sup>-1</sup>·kg<sup>-1</sup>. A Pearson's correlation of r = 0.78 (p < 0.0001) and a standard error of estimate (SEE) of 5.0 ml·min<sup>-1</sup>·kg<sup>-1</sup> were found between methods. At follow-up (n = 52), body mass was reduced by 6.6 ± 1.4 kg (p < 0.0001). V̇O<sub>2</sub>peak increased by 3.3 ± 0.9 ml·min<sup>-1</sup>·kg<sup>-1</sup> and 175 ± 78 ml·min<sup>-1</sup> and SCG eV̇O<sub>2</sub>peak by 2.6 ± 0.8 ml·min<sup>-1</sup>·kg<sup>-1</sup> and 93 ± 76 ml·min<sup>-1</sup> (two-way ANOVA repeated measure: intervention p < 0.0001, method p = 0.939 and interaction p = 0.125, relative V̇O<sub>2</sub>peak). A Pearson's correlation of r = 0.37 (p < 0.05) was found between changes in relative V̇O<sub>2</sub>peak but not for absolute V̇O<sub>2</sub>peak r = 0.10 (p = 0.402).</p><p><strong>Conclusions: </strong>The SCG method is accurate for estimating V̇O<sub>2</sub>peak and appropriate for detecting group changes in both relative and absolute V̇O<sub>2</sub>peak following a lifestyle intervention in people with overweight and obesity. Furthermore, the method can detect individual changes in V̇O<sub>2</sub>peak but not independently of body mass changes. Yet, the applicability is still limited by the relatively large variation in LoA and SEE.</p>\",\"PeriodicalId\":14183,\"journal\":{\"name\":\"International Journal of Obesity\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-01-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Obesity\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41366-025-01713-9\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Obesity","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41366-025-01713-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
摘要
目的：本研究旨在探讨在超重和肥胖人群进行14周生活方式干预前后，非运动状态下静息心电图（scgevo2peak）评估心肺健康的有效性和适用性。方法：研究在一所提供14周生活方式改变课程的Folk高中进行，参与者住在学校，自愿参加日常讲座和活动。67名年龄和体重指数在18 ~ 70岁，25 ~ 50 kg·m-2的男性和女性在基线时进行检测，52名在14周后进行随访检测。测试包括人体测量变量的测定，仰卧休息时的SCG eV o 2峰值，以及在循环测力仪上的金标准V o 2峰值测试，直到自愿精疲力竭。结果：基线（n = 67， SCG eV / o2峰：26.9±1.9 ml·min-1·kg-1， V / o2峰：26.6±1.6 ml·min-1·kg-1，平均值±95%置信区间）的一致性分析显示偏差为0.3±1.0 ml·min-1·kg-1, 95%一致性限（LoA）为±9.8 ml·min-1·kg-1。两种方法之间的Pearson相关性为r = 0.78 （p -1·kg-1）。在随访时（n = 52），体重减少6.6±1.4 kg (p 2峰增加3.3±0.9 ml·min-1·kg-1和175±78 ml·min-1)， SCG eV o 2峰增加2.6±0.8 ml·min-1·kg-1和93±76 ml·min-1（双向方差分析重复测量：干预p 2峰）。皮尔逊相关r = 0.37 (p = 2peak)，但绝对vo_2峰值r = 0.10 （p = 0.402）不相关。结论：SCG法可准确估算出超重和肥胖人群生活方式干预后的相对和绝对V值，适用于检测组间的变化。此外，该方法可以检测个体的V²o2峰值变化，但不能独立于体重变化。然而，由于LoA和SEE变化较大，其适用性仍然受到限制。
V̇O2peak estimation in people with overweight and obesity before and after a 14-week lifestyle intervention.
Purpose: This study aimed to investigate the validity and applicability of a non-exercise estimation of cardiorespiratory fitness using resting seismocardiography (SCG eV̇O2peak) in people with overweight and obesity before and after a 14-week lifestyle intervention.
Methods: The study was carried out at a Folk high school that offers 14-week courses on lifestyle changes where participants live at the school and voluntarily participate in daily lectures and activities. Sixty-seven men and women with age and body mass index between 18 and 70 years and 25-50 kg·m-2 were tested at baseline, and 52 had a follow-up test after 14 weeks. Testing included the determination of anthropometric variables, an SCG eV̇O2peak at supine rest, and a gold standard V̇O2peak test on a cycle ergometer until voluntary exhaustion.
Results: Agreement analysis for V̇O2peak at baseline (n = 67, SCG eV̇O2peak: 26.9 ± 1.9 ml·min-1·kg-1, V̇O2peak: 26.6 ± 1.6 ml·min-1·kg-1, mean ± 95% confidence interval) showed a bias of 0.3 ± 1.0 ml·min-1·kg-1 with 95% limits of agreement (LoA) ranging ± 9.8 ml·min-1·kg-1. A Pearson's correlation of r = 0.78 (p < 0.0001) and a standard error of estimate (SEE) of 5.0 ml·min-1·kg-1 were found between methods. At follow-up (n = 52), body mass was reduced by 6.6 ± 1.4 kg (p < 0.0001). V̇O2peak increased by 3.3 ± 0.9 ml·min-1·kg-1 and 175 ± 78 ml·min-1 and SCG eV̇O2peak by 2.6 ± 0.8 ml·min-1·kg-1 and 93 ± 76 ml·min-1 (two-way ANOVA repeated measure: intervention p < 0.0001, method p = 0.939 and interaction p = 0.125, relative V̇O2peak). A Pearson's correlation of r = 0.37 (p < 0.05) was found between changes in relative V̇O2peak but not for absolute V̇O2peak r = 0.10 (p = 0.402).
Conclusions: The SCG method is accurate for estimating V̇O2peak and appropriate for detecting group changes in both relative and absolute V̇O2peak following a lifestyle intervention in people with overweight and obesity. Furthermore, the method can detect individual changes in V̇O2peak but not independently of body mass changes. Yet, the applicability is still limited by the relatively large variation in LoA and SEE.
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