泰国归国后可杜沟沙门氏菌引起细菌性肠炎1例。

IF 1.9 4区 医学 Q3 INFECTIOUS DISEASES Journal of Infection and Chemotherapy Pub Date : 2025-01-17 DOI:10.1016/j.jiac.2025.102625
Nobumasa Okumura, Rika Yamamoto, Nana Akazawa-Kai, Kaori Tsuge, Misako Ohkusu, Naruhiko Ishiwada, Naoya Itoh
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引用次数: 0

摘要

非伤寒沙门氏菌(NTS)包括许多血清型,其宿主、地理分布和毒力不同。我们报告一例64岁男子从泰国返回后无菌血症发生由克杜古沙门氏菌引起的肠炎。该患者为打高尔夫球在泰国清迈停留了10天,并在返回日本当天因发烧、发冷、水样腹泻和呕吐而住院。患者静脉滴注阿奇霉素,随后加用头孢曲松治疗6 d。在患者的粪便培养中检测到NTS,并进行了额外的菌株分析。o抗原聚合酶链反应及fliC和fliB基因序列分析确定菌株血清型为O13: i: 1,w。通过多位点序列分型鉴定菌株为1543型。这些结果证实菌株是S. Kedougou。考虑到沙门氏菌病的潜伏期,该患者极有可能在泰国感染了S. Kedougou,这与泰国北部经常发现S. Kedougou的流行病学信息相一致。NTS血清型的鉴定可能不会影响临床管理;然而,我们认为积累流行病学信息对于了解环境、动物和人类之间的相互作用是重要的。
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Bacterial enteritis caused by Salmonella Kedougou after returning from Thailand: A case report.

Non-typhoid Salmonella (NTS) includes many serotypes that differ in host, geographic distribution, and virulence. We report the case of a 64-year-old man who developed enteritis caused by Salmonella Kedougou without bacteremia after returning from Thailand. The patient stayed in Chiang Mai, Thailand, for 10 days to play golf and was hospitalized with fever, chills, watery diarrhea, and vomiting on the day the patient returned to Japan. The patient was treated with intravenous azithromycin followed by ceftriaxone for 6 days. NTS was detected in the patient's stool culture, and additional strain analyses were performed. Polymerase chain reaction for the O-antigen and sequence analysis of fliC and fliB genes determined the serotype of the strain to be O13: i: l,w. The strain was assigned to sequence type 1543 using multilocus sequence typing. These results confirmed that the strain was S. Kedougou. Considering the incubation period of salmonellosis, the patient was most likely infected with S. Kedougou in Thailand, which is consistent with the epidemiological information that S. Kedougou is frequently detected in northern Thailand. The identification of NTS serovars may not affect clinical management; however, we believe that it is important to accumulate epidemiological information to understand the interactions between the environment, animals, and humans.

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来源期刊
Journal of Infection and Chemotherapy
Journal of Infection and Chemotherapy INFECTIOUS DISEASES-PHARMACOLOGY & PHARMACY
CiteScore
4.10
自引率
4.50%
发文量
303
审稿时长
47 days
期刊介绍: The Journal of Infection and Chemotherapy (JIC) — official journal of the Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases — welcomes original papers, laboratory or clinical, as well as case reports, notes, committee reports, surveillance and guidelines from all parts of the world on all aspects of chemotherapy, covering the pathogenesis, diagnosis, treatment, and control of infection, including treatment with anticancer drugs. Experimental studies on animal models and pharmacokinetics, and reports on epidemiology and clinical trials are particularly welcome.
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