用于干细胞储存的人类牙齿生物银行:保存干细胞以备将来需要。

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Journal of the Pakistan Medical Association Pub Date : 2025-01-01 DOI:10.47391/JPMA.20013
Saqib Habib, Shahrukh Ali Khan, Aqeel Ahmed, Farhan Raza Khan
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引用次数: 0

摘要

人类牙齿是胚胎后牙间充质干细胞的潜在储存库。研究人员已经从牙髓和牙周韧带组织中鉴定并分离出7种类型的牙干细胞。这些细胞由于其增加的增殖性质,在医学和牙科领域具有广泛的临床应用。生物银行是储存人体生物组织以保存和分离干细胞的概念。到目前为止,造血组织一直是生物银行设施关注的领域。摘出的人牙可以作为分离和保存牙干细胞的宝贵资源,用于未来的治疗效益。目前的叙述综述计划集中在牙齿生物银行过程的工作流程,其分离,冷冻保存,以及在医疗和牙科专业的潜在治疗用途xx。
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Biobanking of human teeth for stem cell storage: Preserving stem cells for future needs.

Human teeth serves as a potential reservoir for postembryonic mesenchymal dental stem cells. Researchers have identified and isolated seven types of dental stem cells from pulp and periodontal ligament tissues. These cells have a wide range of clinical applications across the fields of medicine and dentistry due to their increased proliferative nature. Biobanking is a concept for storing human biological tissues to preserve and isolate stem cells. Until now, haematopoietic tissues have been the area of focus for biobanking facilities. Extracted human teeth may serve as a valuable resource for the isolation and preservation of dental stem cells for future therapeutic benefits. The current narrative review was planned to focus on the workflow of the teeth biobanking process, its isolation, cryopreservation, and potential therapeutic uses in medical and dental specialtiesxx.

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来源期刊
CiteScore
1.10
自引率
11.10%
发文量
983
审稿时长
3-6 weeks
期刊介绍: Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.
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