在光学相干层析成像中实现高精度衰减系数测量。

Journal of biophotonics Pub Date : 2025-01-16 DOI:10.1002/jbio.202400395

Linda B Neubrand, Xavier Attendu, Ton G van Leeuwen

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摘要

在这项研究中，我们的目标是利用1310 nm光学相干层析成像（OCT）系统验证用于确定衰减系数的解析性Cramer-Rao下界（CRLB）方程。我们的实验结果成功地证实了方程的有效性，在脂质内样品的标准偏差低于0.01 mm-1的情况下实现了前所未有的精度。此外，我们还介绍了一种用于实现高精度OCT衰减测量的系统框架。

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Achieving High-Precision Attenuation Coefficient Measurement in Optical Coherence Tomography.

In this study, we aim to validate the analytical Cramer-Rao lower bound (CRLB) equation for determining attenuation coefficients using a 1310 nm Optical Coherence Tomography (OCT) system. Our experimental results successfully confirm the validity of the equation, achieving unprecedented precision with a standard deviation below 0.01 mm^-1 for intralipid samples. Furthermore, we introduce a systematic framework for attaining high precision in OCT attenuation measurements.

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Journal of biophotonics

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