Delphi共识对西班牙脑卒中后偏瘫肩痛患者用A型肉毒毒素治疗的治疗:结果研究。

IF 4 3区 医学 Q2 FOOD SCIENCE & TECHNOLOGY Toxins Pub Date : 2025-01-16 DOI:10.3390/toxins17010040
Carlos Cordero-García, Irene de Torres, Jacobo Formigo-Couceiro, Lluis Guirao, Mª Dolores Romero-Torres, Sergio Otero-Villaverde, Alberto Herrera, Cristina Santa, Antonio Mena-Rodriguez
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引用次数: 0

摘要

该研究旨在确定专家意见并获得中风后偏瘫肩痛(HSP)的管理和肉毒毒素A (BoNT-A)治疗的建议。一项多中心德尔福研究采用在线调查进行,该调查由一个专家委员会设计,该委员会在西班牙使用BoNT-A进行脑卒中后HSP管理方面至少有10年的经验。47名小组成员(具有至少5年BoNT-A卒中后HSP管理经验的专家)根据≥66.7%的接受度对他们的同意程度进行了两轮评分。在第1245轮中,对三个维度的陈述进行了评估(BoNT-A治疗的HSP患者的诊断、治疗和随访)。第2轮后,共有159人(70.9%)最终被接受。专家建议,一旦痉挛影响到日常活动,就进行BoNT-A治疗。他们认为超声是首选的引导技术。专家建议使用有效的量表和患者报告的结果进行定期评估,以评估治疗目标和安全性。如果没有效果,专家们建议增加治疗肌肉的剂量或数量,或考虑其他治疗方法。这些基于共识的建议为临床医生提供了一种用BoNT-A治疗脑卒中后HSP的方法,支持明智的决策。
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Delphi Consensus on the Management of Spanish Patients with Post-Stroke Hemiplegic Shoulder Pain Treated with Botulinum Toxin A: Result Study.

The study aimed to identify expert opinions and obtain recommendations on the management of post-stroke hemiplegic shoulder pain (HSP) and treatment with botulinum toxin A (BoNT-A). A multicenter Delphi study was conducted using an online survey designed by a committee of experts with at least 10 years of experience in post-stroke HSP management with BoNT-A in Spain. Forty-seven panelists (specialists with at least 5 years of experience in post-stroke HSP management with BoNT-A) rated their level of agreement in two rounds based on acceptance by ≥66.7% of them. In round 1, 245 statements on three dimensions were evaluated (diagnosis, treatment, and follow-up of the HSP patients treated with BoNT-A). A total of 159 statements (70.9%) were finally accepted after round 2. Experts recommended BoNT-A as soon as spasticity affects daily activities. They considered ultrasound as the preferred guided technique. Experts recommended regular assessments using validated scales and patient-reported outcomes to evaluate treatment goals and safety. In case of lack of response, experts suggested increasing the dose or number of treated muscles or considering alternative treatments. These consensus-based recommendations offer clinicians an approach to the management of post-stroke HSP with BoNT-A, supporting informed decision making.

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来源期刊
Toxins
Toxins TOXICOLOGY-
CiteScore
7.50
自引率
16.70%
发文量
765
审稿时长
16.24 days
期刊介绍: Toxins (ISSN 2072-6651) is an international, peer-reviewed open access journal which provides an advanced forum for studies related to toxins and toxinology. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
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