氧化应激在乳腺癌发生、发展和治疗中的作用。

IF 6.6 2区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Antioxidants Pub Date : 2025-01-17 DOI:10.3390/antiox14010104

Rui Dong, Jing Wang, Ruiqi Guan, Jianwei Sun, Ping Jin, Junling Shen

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引用次数: 0

摘要

乳腺癌是世界上最常见的癌症之一。最近的研究越来越强调氧化应激在乳腺癌的发生和发展中的作用。本文综述了氧化应激失衡如何影响乳腺癌的发生和发展，阐明了活性氧（ROS）在这一背景下运作的复杂机制及其潜在的治疗应用。通过强调这些关键的见解，本综述旨在加强我们对氧化应激作为乳腺癌管理创新治疗策略的潜在靶点的理解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer.

Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer.

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来源期刊

Antioxidants Biochemistry, Genetics and Molecular Biology-Physiology

CiteScore

10.60

自引率

11.40%

发文量

2123

审稿时长

16.3 days

期刊介绍： Antioxidants (ISSN 2076-3921), provides an advanced forum for studies related to the science and technology of antioxidants. It publishes research papers, reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.