基于临床问卷数据的实体增强BERT医学专业预测。

IF 2.6 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES PLoS ONE Pub Date : 2025-01-30 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0317795
Soyeon Lee, Ye Ji Han, Hyun Joon Park, Byung Hoon Lee, DaHee Son, SoYeon Kim, HyeonJong Yang, TaeJun Han, EunSun Kim, Sung Won Han
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引用次数: 0

摘要

远程诊断的医学专科预测系统可以减少首次就诊的患者因症状而到错误的医院科室就诊所产生的意外费用。为了开发医学专业预测系统,一些研究人员探索了使用真实医学文本数据的临床预测模型。医学文本数据包含大量关于患者的信息,这增加了序列长度。因此,一些研究试图从文本中提取实体作为简洁的特征,并为临床文本分类提供特定领域的知识。然而,将它们有效地注入到模型中仍然是不够的。因此,我们提出实体增强BERT (E-BERT),它利用BERT的结构属性进行医学专业预测。E-BERT具有实体嵌入层和实体感知关注,以注入特定领域的知识,并关注序列中医疗相关实体之间的关系。临床问卷数据的实验结果表明,无论输入序列长度如何,E-BERT都优于其他基准模型。此外,实体感知注意效果的可视化结果证明,E-BERT有效地融合了特定领域的知识和其他信息,从而能够捕获文本中的上下文信息。最后,通过将该方法应用于其他预训练语言模型,探讨了该方法的鲁棒性和适用性。这些有效的医学专科预测模型可以为初诊患者提供实用信息,从而简化诊断流程,提高医疗咨询质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Entity-enhanced BERT for medical specialty prediction based on clinical questionnaire data.

A medical specialty prediction system for remote diagnosis can reduce the unexpected costs incurred by first-visit patients who visit the wrong hospital department for their symptoms. To develop medical specialty prediction systems, several researchers have explored clinical predictive models using real medical text data. Medical text data include large amounts of information regarding patients, which increases the sequence length. Hence, a few studies have attempted to extract entities from the text as concise features and provide domain-specific knowledge for clinical text classification. However, it is still insufficient to inject them into the model effectively. Thus, we propose Entity-enhanced BERT (E-BERT), which utilizes the structural attributes of BERT for medical specialty prediction. E-BERT has an entity embedding layer and entity-aware attention to inject domain-specific knowledge and focus on relationships between medical-related entities within the sequences. Experimental results on clinical questionnaire data demonstrate the superiority of E-BERT over the other benchmark models, regardless of the input sequence length. Moreover, the visualization results for the effects of entity-aware attention prove that E-BERT effectively incorporate domain-specific knowledge and other information, enabling the capture of contextual information in the text. Finally, the robustness and applicability of the proposed method is explored by applying it to other Pre-trained Language Models. These effective medical specialty predictive model can provide practical information to first-visit patients, resulting in streamlining the diagnostic process and improving the quality of medical consultations.

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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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