果胶有助于缓解桃子过敏

IF 3.9 3区 农林科学 Q1 VETERINARY SCIENCES Lab Animal Pub Date : 2025-02-03 DOI:10.1038/s41684-025-01509-4
Jorge Ferreira
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引用次数: 0

摘要

食物过敏是一种常见的免疫反应,其症状可以从轻微的不适到危及生命的情况。在日本和地中海地区,桃子过敏是一种常见的食物过敏,这种过敏仍然没有可用的免疫疗法。《科学报告》上的一项研究研究了在对桃皮提取物敏感的CBA/J小鼠的饮食中补充膳食纤维果胶的效果。与对照过敏动物相比,在饮食中添加果胶并不能防止接触桃子提取物的小鼠出现与过敏相关的临床症状。然而,与过敏对照组的动物相比,果胶治疗的动物显示出大肠和盲肠的长度增加。果胶处理个体表现出微生物丰富度和复杂性的降低。同样,与过敏对照组相比,果胶组显示出免疫反应相关细胞的减少。因此,这些结果表明果胶在食物过敏的表现中起着有益的作用,改变免疫反应,促进免疫耐受并提供抗炎特性。原始文献:Steigerwald, H. et al。科学。众议员14,30503 (2024)
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来源期刊
Lab Animal
Lab Animal 农林科学-兽医学
CiteScore
0.60
自引率
2.90%
发文量
181
审稿时长
>36 weeks
期刊介绍: LabAnimal is a Nature Research journal dedicated to in vivo science and technology that improves our basic understanding and use of model organisms of human health and disease. In addition to basic research, methods and technologies, LabAnimal also covers important news, business and regulatory matters that impact the development and application of model organisms for preclinical research. LabAnimal's focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.
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