脑血管疾病药物控制释放系统

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY Advanced Therapeutics Pub Date : 2024-10-08 DOI:10.1002/adtp.202400239
Celia Martín-Morales, Sofia Caspani, Manuel Desco, Célia Tavares de Sousa, María Victoria Gómez-Gaviro
{"title":"脑血管疾病药物控制释放系统","authors":"Celia Martín-Morales,&nbsp;Sofia Caspani,&nbsp;Manuel Desco,&nbsp;Célia Tavares de Sousa,&nbsp;María Victoria Gómez-Gaviro","doi":"10.1002/adtp.202400239","DOIUrl":null,"url":null,"abstract":"<p>This review offers a comprehensive exploration of optimized drug delivery systems tailored for controlled release and their crucial role in addressing cerebrovascular diseases. Through an in-depth analysis, various controlled release methods, including nanoparticles, liposomes, hydrogels, and other emerging technologies are examined. Highlighting the importance of precise drug targeting, it is delved into the underlying mechanisms of these delivery systems and their potential to improve therapeutic outcomes while minimizing adverse effects. Additionally, the specific applications of these optimized drug delivery systems in treating cerebrovascular disorders such as ischemic stroke, cerebral aneurysms, and intracranial hemorrhage are discussed. By shedding light on the advancements in drug delivery techniques and their implications in cerebrovascular medicine, this review offers valuable insights into the future of therapeutic interventions in neurology.</p>","PeriodicalId":7284,"journal":{"name":"Advanced Therapeutics","volume":"8 1","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adtp.202400239","citationCount":"0","resultStr":"{\"title\":\"Controlled Drug Release Systems for Cerebrovascular Diseases\",\"authors\":\"Celia Martín-Morales,&nbsp;Sofia Caspani,&nbsp;Manuel Desco,&nbsp;Célia Tavares de Sousa,&nbsp;María Victoria Gómez-Gaviro\",\"doi\":\"10.1002/adtp.202400239\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This review offers a comprehensive exploration of optimized drug delivery systems tailored for controlled release and their crucial role in addressing cerebrovascular diseases. Through an in-depth analysis, various controlled release methods, including nanoparticles, liposomes, hydrogels, and other emerging technologies are examined. Highlighting the importance of precise drug targeting, it is delved into the underlying mechanisms of these delivery systems and their potential to improve therapeutic outcomes while minimizing adverse effects. Additionally, the specific applications of these optimized drug delivery systems in treating cerebrovascular disorders such as ischemic stroke, cerebral aneurysms, and intracranial hemorrhage are discussed. By shedding light on the advancements in drug delivery techniques and their implications in cerebrovascular medicine, this review offers valuable insights into the future of therapeutic interventions in neurology.</p>\",\"PeriodicalId\":7284,\"journal\":{\"name\":\"Advanced Therapeutics\",\"volume\":\"8 1\",\"pages\":\"\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adtp.202400239\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Therapeutics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adtp.202400239\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Therapeutics","FirstCategoryId":"3","ListUrlMain":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adtp.202400239","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

摘要

本文综述了为控制释放量身定制的优化药物递送系统及其在治疗脑血管疾病中的重要作用的全面探索。通过深入分析,各种控释方法,包括纳米颗粒、脂质体、水凝胶和其他新兴技术进行了研究。它强调了精确药物靶向的重要性,深入研究了这些输送系统的潜在机制及其在改善治疗结果的同时最大限度地减少不良反应的潜力。此外,还讨论了这些优化的药物输送系统在治疗缺血性中风、脑动脉瘤和颅内出血等脑血管疾病中的具体应用。通过阐明药物传递技术的进展及其在脑血管医学中的意义,本综述为神经病学治疗干预的未来提供了有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

摘要图片

摘要图片

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Controlled Drug Release Systems for Cerebrovascular Diseases

This review offers a comprehensive exploration of optimized drug delivery systems tailored for controlled release and their crucial role in addressing cerebrovascular diseases. Through an in-depth analysis, various controlled release methods, including nanoparticles, liposomes, hydrogels, and other emerging technologies are examined. Highlighting the importance of precise drug targeting, it is delved into the underlying mechanisms of these delivery systems and their potential to improve therapeutic outcomes while minimizing adverse effects. Additionally, the specific applications of these optimized drug delivery systems in treating cerebrovascular disorders such as ischemic stroke, cerebral aneurysms, and intracranial hemorrhage are discussed. By shedding light on the advancements in drug delivery techniques and their implications in cerebrovascular medicine, this review offers valuable insights into the future of therapeutic interventions in neurology.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Advanced Therapeutics
Advanced Therapeutics Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
7.10
自引率
2.20%
发文量
130
期刊最新文献
High-Efficiency, Short-Pulse Electrothermal Cancer Therapy Utilizing Polyethylene Glycol (PEG-) Based Titanium Carbide (Ti3C2) MXene Nanomaterials Targeting Ferroptosis for Cancer Immunotherapy: Molecular Mechanisms, Immune Microenvironment Crosstalk, and Clinical Translation Prospects High-Efficiency, Short-Pulse Electrothermal Cancer Therapy Utilizing Polyethylene Glycol (PEG-) Based Titanium Carbide (Ti3C2) MXene Nanomaterials Targeting Ferroptosis for Cancer Immunotherapy: Molecular Mechanisms, Immune Microenvironment Crosstalk, and Clinical Translation Prospects Light-Triggered Antibody-Photosensitizer Conjugates Disrupt P-Glycoprotein Function to Reverse Multidrug Resistance
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1