Cas13a-RPA测量描述了血浆circWDR37在结直肠癌中的潜在作用

IF 13.7 Q1 CHEMISTRY, MULTIDISCIPLINARY Aggregate (Hoboken, N.J.) Pub Date : 2025-01-21 DOI:10.1002/agt2.739
Jingsong Xu, Li Cao, Shuang Yang, Ying Jian, Yu Liu, Zhen Shen, Qian Liu, Xiang Chen, Min Li, Shun Li, Xiaolei Zuo, Min Li, Hua Wang
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摘要

本研究发现circWDR37是一种有希望用于结直肠癌(CRC)早期诊断和预后预测的生物标志物。利用聚乙二醇8000和右旋糖酐-10增强荧光,提高检测灵敏度,建立了μDCR检测平台。预计μDCR将成为无创CRC筛查的最佳方法(e663)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Back Cover: Droplets Cas13a-RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer

This study identified circWDR37 as a promising biomarker for the early diagnosis and prognostic prediction of colorectal cancer (CRC). A detection platform, termed μDCR, was developed utilizing polyethylene glycol 8000 and dextran-10 to enhance fluorescence and improve detection sensitivity. It is anticipated that μDCR will serve as an optimal method for noninvasive CRC screening (e663).

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