Synthesis and Spectral Studies of Iron-Catalyzed Multicomponent Synthesis of 4‑Phosphorylated 4H‑Chromenes from 2-Hydroxybenzyl Alcohols

A facile, mild, effective, and multicomponent protocol for the production of 4‑phosphorylated-4H‑chromenes through an aldol condensation, Michael addition, and cyclization was established. The C─C, C─P, and C─O bonds were constructed during the reaction to produce the desired product from 2-hydroxybenzyl alcohols. The synthesized compounds were characterized by standard techniques. The important features of this protocol are operational simplicity, moderate reaction conditions, the use of a low-cost iron complex, and high atom economy.