Abumelha S , Alkhayal A , Alrabeeah K , Alrashed M , Almasari R , Aloudah N
{"title":"滑膜肉瘤：首次出现于阴部交界处1例","authors":"Abumelha S , Alkhayal A , Alrabeeah K , Alrashed M , Almasari R , Aloudah N","doi":"10.1016/j.eucr.2025.102946","DOIUrl":null,"url":null,"abstract":"<div><div>Synovial sarcoma is a rare malignant tumour that arises from mesenchymal origin. This case is about <u>synovial</u> sarcoma in unusual place, the scrotum and penile shaft. A 36-year-old man presented with a tender penoscrotal mass for 5 years. The patient underwent surgical resection of the mass. Histopathology revealed cellular spindle cell tumour arranged into interlacing fascicle, Immunohistochemistry analysis revealed a positive TLE-1, CD99, B-cell lymphoma 2 (BLC2), Focal cytokeratin and focal epithelial membrane antigen (EMA). In our case, the patient was aggressively treated with two surgical resections and still progressed and metastasized and continued progressing even after different chemotherapy regimens.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"59 ","pages":"Article 102946"},"PeriodicalIF":0.5000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synovial sarcoma: A case report of first presentation at penoscrotal junction\",\"authors\":\"Abumelha S , Alkhayal A , Alrabeeah K , Alrashed M , Almasari R , Aloudah N\",\"doi\":\"10.1016/j.eucr.2025.102946\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Synovial sarcoma is a rare malignant tumour that arises from mesenchymal origin. This case is about <u>synovial</u> sarcoma in unusual place, the scrotum and penile shaft. A 36-year-old man presented with a tender penoscrotal mass for 5 years. The patient underwent surgical resection of the mass. Histopathology revealed cellular spindle cell tumour arranged into interlacing fascicle, Immunohistochemistry analysis revealed a positive TLE-1, CD99, B-cell lymphoma 2 (BLC2), Focal cytokeratin and focal epithelial membrane antigen (EMA). In our case, the patient was aggressively treated with two surgical resections and still progressed and metastasized and continued progressing even after different chemotherapy regimens.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"59 \",\"pages\":\"Article 102946\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025000178\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025000178","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/15 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Synovial sarcoma: A case report of first presentation at penoscrotal junction
Synovial sarcoma is a rare malignant tumour that arises from mesenchymal origin. This case is about synovial sarcoma in unusual place, the scrotum and penile shaft. A 36-year-old man presented with a tender penoscrotal mass for 5 years. The patient underwent surgical resection of the mass. Histopathology revealed cellular spindle cell tumour arranged into interlacing fascicle, Immunohistochemistry analysis revealed a positive TLE-1, CD99, B-cell lymphoma 2 (BLC2), Focal cytokeratin and focal epithelial membrane antigen (EMA). In our case, the patient was aggressively treated with two surgical resections and still progressed and metastasized and continued progressing even after different chemotherapy regimens.
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