{"title":"一些苯并咪唑、苯并恶唑、苯并噻唑-甲基磺胺-4-芳基-1,4-二氢嘧啶-5-碳腈衍生物的合成、表征和抗菌活性研究","authors":"Die Rachelle Celiane , Ambeu-Loko N’ta Christelle Mélissa , Fante Bamba , Hiebel Marie-Aude , Suzenet Franck , Vallin Aurélie , Chagnault Vincent","doi":"10.1080/10426507.2024.2424275","DOIUrl":null,"url":null,"abstract":"<div><div>We synthetized some methylsulfanyl-4-aryl-1,4-dihydropyrimidine-5-carbonitriles derivatives coupled with benzimidazole, benzoxazole, and benzothiazole rings. Some of these compounds exhibit antibacterial activity, particularly against gram-positive bacteria such as <em>Enterococcus faecalis</em> (<strong>6e</strong>) and <em>Staphylococcus aureus</em> (<strong>4f</strong>, <strong>6b</strong>, <strong>6i</strong>, and <strong>8a</strong>).</div></div>","PeriodicalId":20056,"journal":{"name":"Phosphorus, Sulfur, and Silicon and the Related Elements","volume":"199 7","pages":"Pages 814-823"},"PeriodicalIF":1.3000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis, characterization, and antimicrobial activity of some benzimidazolyl, benzoxazolyl, benzothiazolyl-methylsulfanyl-4-aryl-1,4-dihydropyrimidine-5-carbonitrile derivatives\",\"authors\":\"Die Rachelle Celiane , Ambeu-Loko N’ta Christelle Mélissa , Fante Bamba , Hiebel Marie-Aude , Suzenet Franck , Vallin Aurélie , Chagnault Vincent\",\"doi\":\"10.1080/10426507.2024.2424275\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We synthetized some methylsulfanyl-4-aryl-1,4-dihydropyrimidine-5-carbonitriles derivatives coupled with benzimidazole, benzoxazole, and benzothiazole rings. Some of these compounds exhibit antibacterial activity, particularly against gram-positive bacteria such as <em>Enterococcus faecalis</em> (<strong>6e</strong>) and <em>Staphylococcus aureus</em> (<strong>4f</strong>, <strong>6b</strong>, <strong>6i</strong>, and <strong>8a</strong>).</div></div>\",\"PeriodicalId\":20056,\"journal\":{\"name\":\"Phosphorus, Sulfur, and Silicon and the Related Elements\",\"volume\":\"199 7\",\"pages\":\"Pages 814-823\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phosphorus, Sulfur, and Silicon and the Related Elements\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1042650724000662\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/1 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, INORGANIC & NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phosphorus, Sulfur, and Silicon and the Related Elements","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1042650724000662","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/1 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
Synthesis, characterization, and antimicrobial activity of some benzimidazolyl, benzoxazolyl, benzothiazolyl-methylsulfanyl-4-aryl-1,4-dihydropyrimidine-5-carbonitrile derivatives
We synthetized some methylsulfanyl-4-aryl-1,4-dihydropyrimidine-5-carbonitriles derivatives coupled with benzimidazole, benzoxazole, and benzothiazole rings. Some of these compounds exhibit antibacterial activity, particularly against gram-positive bacteria such as Enterococcus faecalis (6e) and Staphylococcus aureus (4f, 6b, 6i, and 8a).
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Phosphorus, Sulfur, and Silicon and the Related Elements is a monthly publication intended to disseminate current trends and novel methods to those working in the broad and interdisciplinary field of heteroatom chemistry.
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