基于k-mer的KNN模型的物种注释。

IF 1.9 Bioinformation Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI:10.6026/973206300200986
Srushti Sangar, Prathamesh Kolage, Pritee Chunarkar-Patil
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引用次数: 0

摘要

细菌鉴定是微生物学、临床诊断、环境监测和食品安全的关键过程。通过提高准确性、速度和可扩展性,机器学习有望改善细菌鉴定。但是,必须解决数据依赖性、模型可解释性和计算需求等挑战,才能充分实现它的潜力。基于K-mer的细菌鉴定算法是解决这些问题的一种尝试。序列匹配使用KNN技术完成。这包括特征提取、数据集准备、分类器训练和基于k-mer频率分布相似度的标签预测。该算法的性能通过F1分数和精度等准确性评估指标进行了交叉检验,准确率达到了令人印象深刻的93%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Species annotation using a k-mer based KNN model.

Bacterial identification is a critical process in microbiology, clinical diagnostics, environmental monitoring, and food safety. Machine learning holds great promise for improving bacterial identification by increasing accuracy, speed, and scalability. However, challenges such as data dependency, model interpretability, and computational demands must be addressed to fully realize it's potential. k-mer based bacterial identification algorithm is an attempt to address these issues. Sequence matching is completed using the KNN technique. This included feature extraction, dataset preparation, classifier training, and label prediction based on k-mer frequency distribution similarity. The algorithm's performance has been cross-checked through accuracy assessment metrics such as F1 score and precision with an impressive 93% accuracy rate.

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Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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128
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