一种利用ninps - zif -8修饰电极的新型电化学传感器，用于实际样品中维生素D3的检测

IF 3.1 3区化学 Q3 CHEMISTRY, PHYSICAL Chemical Physics Letters Pub Date : 2025-04-16 Epub Date: 2025-02-03 DOI:10.1016/j.cplett.2025.141936

Konda Bindu , Tummala Anusha , Pradeep Kumar Brahman

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引用次数: 0

摘要

合成了一种基于镍纳米颗粒（NiNPs）和沸石咪唑酸框架-8 （ZIF-8）的高灵敏度检测平台，用于维生素D3的定量测定。利用各种表面和电化学技术研究了制备电极的物理特性和行为。在最佳条件下，NiNPs-ZIF-8@GCE的动态范围为0.025 ~ 25 μM，检测限为0.002 μM。此外，超灵敏的维生素D3传感器具有可接受的重复性，满意的特异性，良好的储存稳定性和高灵敏度。最终，该传感器成功检测了生物样品中不同浓度的维生素D3，证实了其实用性。

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A novel electrochemical sensor for vitamin D3 detection in real samples using NiNPs-ZIF-8-modified electrode

A highly sensitive sensing platform based on nickel nanoparticles (NiNPs) and zeolitic imidazolate framework-8 (ZIF-8) was synthesized for quantitative measurement of vitamin D₃. The physical characteristics and behaviour of the fabricated electrode were investigated using various surface and electrochemical techniques. Under optimal conditions, the NiNPs-ZIF-8@GCE demonstrated a broad dynamic range from 0.025 to 25 μM with a detection limit of 0.002 μM. Moreover, the ultrasensitive vitamin D₃ sensor displayed acceptable reproducibility, satisfactory specificity, good storage stability, and high sensitivity. Ultimately, the proposed sensor successfully detects various concentrations of vitamin D₃ in biological samples, affirming its practical applicability.

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来源期刊

Chemical Physics Letters 化学-物理：原子、分子和化学物理

CiteScore

5.70

自引率

3.60%

发文量

798

审稿时长

33 days

期刊介绍： Chemical Physics Letters has an open access mirror journal, Chemical Physics Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Chemical Physics Letters publishes brief reports on molecules, interfaces, condensed phases, nanomaterials and nanostructures, polymers, biomolecular systems, and energy conversion and storage. Criteria for publication are quality, urgency and impact. Further, experimental results reported in the journal have direct relevance for theory, and theoretical developments or non-routine computations relate directly to experiment. Manuscripts must satisfy these criteria and should not be minor extensions of previous work.