{"title":"髂内动脉瘤血管内修复术中支架闭塞的影响因素。","authors":"Corinna Walter MD, Miriam Kliewer MD, Fadi Taher MD, Afshin Assadian MD","doi":"10.1016/j.jvs.2025.01.224","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate technical factors influencing stent graft occlusion following endovascular repair of internal iliac artery aneurysms (IIAAs), with a specific focus on the longitudinal length of unsupported stent graft segments and connecting stent grafts.</div></div><div><h3>Methods</h3><div>A retrospective single-center analysis was performed on 61 IIAAs treated with endovascular techniques between 2010 and 2022. Anatomical and technical factors, including the unsupported stent graft length within the aneurysm sac (Distance A) and the length of the distal sealing zone (Distance B), were assessed. Statistical analyses were conducted to identify factors associated with stent graft occlusion, type Ib endoleaks, and clinical outcomes.</div></div><div><h3>Results</h3><div>The primary technical success rate was 90.2%, with a stent graft occlusion rate of 23% documented over a mean follow-up period of 25.7 months. A longer unsupported stent graft length (Distance A) was significantly associated with increased risk of occlusion (53.7 vs 37.0 mm in nonoccluded cases; <em>P</em> = .017). Occlusion rates were also higher in cases with a greater number of connecting stent grafts used to extend the iliac branched device to healthy vessel segments (<em>P</em> = .015). Type Ib endoleaks occurred in 6.6% of cases and were significantly associated with shorter distal sealing zones (≤15 mm; odds ratio, 18.0). Despite these technical challenges, clinical success was achieved in 83.3% over the follow-up period, with low rates of ischemic complications. Buttock claudication occurred in 12.9% of cases, and erectile dysfunction was reported in one patient.</div></div><div><h3>Conclusions</h3><div>Endovascular repair of IIAAs is effective and provides a viable option for patients unfit for open surgery. However, it carries risks of stent graft occlusion and endoleaks, particularly when the unsupported stent graft length is extended or when multiple connecting stents are used. Optimizing graft configurations and minimizing unsupported segments may reduce occlusion risks. Furthermore, ensuring an adequate distal sealing zone length is critical to minimizing the occurrence of type Ib endoleaks. These findings highlight the importance of careful procedural planning and technical considerations to improve long-term outcomes and enhance durability in endovascular management of IIAAs.</div></div>","PeriodicalId":17475,"journal":{"name":"Journal of Vascular Surgery","volume":"81 6","pages":"Pages 1327-1334"},"PeriodicalIF":3.6000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Factors influencing stent graft occlusion in endovascular repair of internal iliac artery aneurysms\",\"authors\":\"Corinna Walter MD, Miriam Kliewer MD, Fadi Taher MD, Afshin Assadian MD\",\"doi\":\"10.1016/j.jvs.2025.01.224\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>This study aimed to evaluate technical factors influencing stent graft occlusion following endovascular repair of internal iliac artery aneurysms (IIAAs), with a specific focus on the longitudinal length of unsupported stent graft segments and connecting stent grafts.</div></div><div><h3>Methods</h3><div>A retrospective single-center analysis was performed on 61 IIAAs treated with endovascular techniques between 2010 and 2022. Anatomical and technical factors, including the unsupported stent graft length within the aneurysm sac (Distance A) and the length of the distal sealing zone (Distance B), were assessed. Statistical analyses were conducted to identify factors associated with stent graft occlusion, type Ib endoleaks, and clinical outcomes.</div></div><div><h3>Results</h3><div>The primary technical success rate was 90.2%, with a stent graft occlusion rate of 23% documented over a mean follow-up period of 25.7 months. A longer unsupported stent graft length (Distance A) was significantly associated with increased risk of occlusion (53.7 vs 37.0 mm in nonoccluded cases; <em>P</em> = .017). Occlusion rates were also higher in cases with a greater number of connecting stent grafts used to extend the iliac branched device to healthy vessel segments (<em>P</em> = .015). Type Ib endoleaks occurred in 6.6% of cases and were significantly associated with shorter distal sealing zones (≤15 mm; odds ratio, 18.0). Despite these technical challenges, clinical success was achieved in 83.3% over the follow-up period, with low rates of ischemic complications. Buttock claudication occurred in 12.9% of cases, and erectile dysfunction was reported in one patient.</div></div><div><h3>Conclusions</h3><div>Endovascular repair of IIAAs is effective and provides a viable option for patients unfit for open surgery. However, it carries risks of stent graft occlusion and endoleaks, particularly when the unsupported stent graft length is extended or when multiple connecting stents are used. Optimizing graft configurations and minimizing unsupported segments may reduce occlusion risks. Furthermore, ensuring an adequate distal sealing zone length is critical to minimizing the occurrence of type Ib endoleaks. These findings highlight the importance of careful procedural planning and technical considerations to improve long-term outcomes and enhance durability in endovascular management of IIAAs.</div></div>\",\"PeriodicalId\":17475,\"journal\":{\"name\":\"Journal of Vascular Surgery\",\"volume\":\"81 6\",\"pages\":\"Pages 1327-1334\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Vascular Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0741521425002903\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0741521425002903","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/7 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
摘要
目的:本研究旨在评估影响髂内动脉瘤(IIAAs)血管内修复后支架闭塞的技术因素,特别关注无支撑支架段和连接支架的纵向长度。方法:对2010 ~ 2022年61例经血管内技术治疗的iiaa进行回顾性单中心分析。对解剖和技术因素进行评估,包括动脉瘤囊内未支撑的支架长度(距离A)和远端封闭区长度(距离B)。进行统计分析以确定与支架阻塞、Ib型内漏和临床结果相关的因素。结果:初次技术成功率为90.2%,平均随访25.7个月,支架闭塞率为23%。较长的无支架支架长度(距离A)与闭塞风险增加显著相关(53.7 mm对37.0 mm,非闭塞病例,p = 0.017)。在使用更多连接支架将髂分支装置(IBD)扩展到健康血管段的情况下,闭塞率也更高(p = 0.015)。Ib型内漏发生在6.6%的病例中,与较短的远端密封区(≤15 mm, OR 18.0)显著相关。尽管存在这些技术挑战,但在随访期间,临床成功率为83.3%,缺血性并发症发生率较低。12.9%的患者出现臀部跛行,1例患者出现勃起功能障碍。结论:血管内修复iiaa是有效的,为不适合开放手术的患者提供了可行的选择。然而,它存在支架闭塞和内漏的风险,特别是当无支撑的支架长度延长或使用多个连接支架时。优化移植物配置和减少不支持的节段可以减少咬合风险。此外,确保足够的远端密封区长度对于减少Ib型内漏的发生至关重要。这些研究结果强调了仔细的手术计划和技术考虑对于改善长期结果和增强血管内治疗iiaa的持久性的重要性。
Factors influencing stent graft occlusion in endovascular repair of internal iliac artery aneurysms
Objective
This study aimed to evaluate technical factors influencing stent graft occlusion following endovascular repair of internal iliac artery aneurysms (IIAAs), with a specific focus on the longitudinal length of unsupported stent graft segments and connecting stent grafts.
Methods
A retrospective single-center analysis was performed on 61 IIAAs treated with endovascular techniques between 2010 and 2022. Anatomical and technical factors, including the unsupported stent graft length within the aneurysm sac (Distance A) and the length of the distal sealing zone (Distance B), were assessed. Statistical analyses were conducted to identify factors associated with stent graft occlusion, type Ib endoleaks, and clinical outcomes.
Results
The primary technical success rate was 90.2%, with a stent graft occlusion rate of 23% documented over a mean follow-up period of 25.7 months. A longer unsupported stent graft length (Distance A) was significantly associated with increased risk of occlusion (53.7 vs 37.0 mm in nonoccluded cases; P = .017). Occlusion rates were also higher in cases with a greater number of connecting stent grafts used to extend the iliac branched device to healthy vessel segments (P = .015). Type Ib endoleaks occurred in 6.6% of cases and were significantly associated with shorter distal sealing zones (≤15 mm; odds ratio, 18.0). Despite these technical challenges, clinical success was achieved in 83.3% over the follow-up period, with low rates of ischemic complications. Buttock claudication occurred in 12.9% of cases, and erectile dysfunction was reported in one patient.
Conclusions
Endovascular repair of IIAAs is effective and provides a viable option for patients unfit for open surgery. However, it carries risks of stent graft occlusion and endoleaks, particularly when the unsupported stent graft length is extended or when multiple connecting stents are used. Optimizing graft configurations and minimizing unsupported segments may reduce occlusion risks. Furthermore, ensuring an adequate distal sealing zone length is critical to minimizing the occurrence of type Ib endoleaks. These findings highlight the importance of careful procedural planning and technical considerations to improve long-term outcomes and enhance durability in endovascular management of IIAAs.
期刊介绍:
Journal of Vascular Surgery ® aims to be the premier international journal of medical, endovascular and surgical care of vascular diseases. It is dedicated to the science and art of vascular surgery and aims to improve the management of patients with vascular diseases by publishing relevant papers that report important medical advances, test new hypotheses, and address current controversies. To acheive this goal, the Journal will publish original clinical and laboratory studies, and reports and papers that comment on the social, economic, ethical, legal, and political factors, which relate to these aims. As the official publication of The Society for Vascular Surgery, the Journal will publish, after peer review, selected papers presented at the annual meeting of this organization and affiliated vascular societies, as well as original articles from members and non-members.