{"title":"具有光谱选择性的 FeO(OH)-H2O/TiO2 防晒配方，通过成纤维细胞测试促进胶原蛋白的合成","authors":"Xun Zhang, Ximing Wen, Yuling Wang, Fangru Jiang, Yiting Chen, Zhe Liu","doi":"10.1111/jocd.70060","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>To develop a sunscreen formula with spectral selectivity that filters harmful light (280–550 nm) while allowing beneficial light (550–760 nm) to permeate and thus to boost collagen generation.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A variety of sunscreen filters and their combinations were tested for transmittance spectrum. The spectral selectivity was quantified by Selection Index (SI), and the optimal formula was identified. Then, human dermal fibroblasts (HDFs) were subjected to simulated sunlight exposure with the application of this formula. The cell viability and collagen levels were measured post-exposure.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The combination of TiO<sub>2</sub> and FeO(OH)·H<sub>2</sub>O displays spectral selectivity and reaches the optimal SI value at the mixing ratio of 64:36. This mixture, when formulated with traditional UV filters, significantly elevates the level of Collagen I.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>This work uncovers the influence of spectral selectivity on the enhancement of sunscreen performance and proposes a filter combination with spectral selectivity. This formula, when integrated with conventional UV sunscreens, allows for the beneficial effects of sunlight to be more pronounced. This discovery may provide fresh insights for the design of future sunscreen products.</p>\n </section>\n </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 2","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70060","citationCount":"0","resultStr":"{\"title\":\"Sunscreen Formula of FeO(OH)·H2O/TiO2 With Spectral Selectivity to Enhance Collagen Biosynthesis via Fibroblast Test\",\"authors\":\"Xun Zhang, Ximing Wen, Yuling Wang, Fangru Jiang, Yiting Chen, Zhe Liu\",\"doi\":\"10.1111/jocd.70060\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>To develop a sunscreen formula with spectral selectivity that filters harmful light (280–550 nm) while allowing beneficial light (550–760 nm) to permeate and thus to boost collagen generation.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A variety of sunscreen filters and their combinations were tested for transmittance spectrum. The spectral selectivity was quantified by Selection Index (SI), and the optimal formula was identified. Then, human dermal fibroblasts (HDFs) were subjected to simulated sunlight exposure with the application of this formula. The cell viability and collagen levels were measured post-exposure.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The combination of TiO<sub>2</sub> and FeO(OH)·H<sub>2</sub>O displays spectral selectivity and reaches the optimal SI value at the mixing ratio of 64:36. This mixture, when formulated with traditional UV filters, significantly elevates the level of Collagen I.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>This work uncovers the influence of spectral selectivity on the enhancement of sunscreen performance and proposes a filter combination with spectral selectivity. This formula, when integrated with conventional UV sunscreens, allows for the beneficial effects of sunlight to be more pronounced. This discovery may provide fresh insights for the design of future sunscreen products.</p>\\n </section>\\n </div>\",\"PeriodicalId\":15546,\"journal\":{\"name\":\"Journal of Cosmetic Dermatology\",\"volume\":\"24 2\",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70060\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cosmetic Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70060\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cosmetic Dermatology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70060","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Sunscreen Formula of FeO(OH)·H2O/TiO2 With Spectral Selectivity to Enhance Collagen Biosynthesis via Fibroblast Test
Objective
To develop a sunscreen formula with spectral selectivity that filters harmful light (280–550 nm) while allowing beneficial light (550–760 nm) to permeate and thus to boost collagen generation.
Methods
A variety of sunscreen filters and their combinations were tested for transmittance spectrum. The spectral selectivity was quantified by Selection Index (SI), and the optimal formula was identified. Then, human dermal fibroblasts (HDFs) were subjected to simulated sunlight exposure with the application of this formula. The cell viability and collagen levels were measured post-exposure.
Results
The combination of TiO2 and FeO(OH)·H2O displays spectral selectivity and reaches the optimal SI value at the mixing ratio of 64:36. This mixture, when formulated with traditional UV filters, significantly elevates the level of Collagen I.
Conclusion
This work uncovers the influence of spectral selectivity on the enhancement of sunscreen performance and proposes a filter combination with spectral selectivity. This formula, when integrated with conventional UV sunscreens, allows for the beneficial effects of sunlight to be more pronounced. This discovery may provide fresh insights for the design of future sunscreen products.
期刊介绍：
The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques.
The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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