Faizan Tahir, Tayyab Afghani, Saadullah Ahmad, Amna Manzoor, Fariha Taimur, Sumeya Ali Khan, Muhammad Saad
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Spectrum of metastatic tumours to orbit over the last twenty years in a tertiary care eye hospital-A retrospective study.
Objective: To assess the type and presentation patterns of tumours metastasising to orbit.
Methods: The retrospective study was conducted at the Al Shifa Trust Eye Hospital, Rawalpindi, Pakistan, and comprised data of all patients with orbital metastatic lesions over a 20-year period, from January 1, 2004, to December 31, 2023. Data was analysed using SPSS 22.
Results: Of the 30 patients, 17(56.7%) were males and 13(43.3%) were females. The highest incidence of orbital metastatic disease was among those aged <10 years 9(30%) and >60 years 11(36.7%). Roof was the commonest site of involvement within the orbit 13(43.3%). Proptosis was the main feature at presentation. Diagnosis was made clinically in 14(46.7%) patients and histologically in 16(53.3%). All the 30(100%) cases were referred to the oncology service for further management. Of them, 2(6.7%) patients were lost to follow-up, 20(66.7%) died within one year of diagnosis, and 8 (26.6%) patients were still under treatment.
Conclusions: The diagnosis of orbital metastasis should always be considered for orbital lesions in all age groups, especially in patients with a known cancer elsewhere. Orbital metastasis usually becomes evident at an advanced stage of underlying malignancy, leading to a high mortality rate..
期刊介绍:
Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.