在过去的二十年在三级护理眼科医院转移肿瘤的频谱-回顾性研究。

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Journal of the Pakistan Medical Association Pub Date : 2025-02-01 DOI:10.47391/JPMA.20794
Faizan Tahir, Tayyab Afghani, Saadullah Ahmad, Amna Manzoor, Fariha Taimur, Sumeya Ali Khan, Muhammad Saad
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引用次数: 0

摘要

目的:探讨眼眶转移性肿瘤的类型和表现特点。方法:回顾性研究在巴基斯坦拉瓦尔品第的Al Shifa信托眼科医院进行,包括2004年1月1日至2023年12月31日20年间所有眼眶转移性病变患者的数据。数据采用SPSS 22进行分析。结果:30例患者中,男性17例(56.7%),女性13例(43.3%)。眼眶转移病发病率最高的是60岁11(36.7%)。屋顶是13号轨道内最常见的受累地点(43.3%)。呈现时的主要特征是突出。临床诊断14例(46.7%),病理诊断16例(53.3%)。所有30例(100%)病例均转至肿瘤科进一步治疗。其中失访2例(6.7%),诊断1年内死亡20例(66.7%),仍在治疗的8例(26.6%)。结论:所有年龄组的眼眶病变都应考虑眼眶转移的诊断,特别是在其他地方已知肿瘤的患者。眼眶转移通常在潜在恶性肿瘤的晚期变得明显,导致高死亡率。
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Spectrum of metastatic tumours to orbit over the last twenty years in a tertiary care eye hospital-A retrospective study.

Objective: To assess the type and presentation patterns of tumours metastasising to orbit.

Methods: The retrospective study was conducted at the Al Shifa Trust Eye Hospital, Rawalpindi, Pakistan, and comprised data of all patients with orbital metastatic lesions over a 20-year period, from January 1, 2004, to December 31, 2023. Data was analysed using SPSS 22.

Results: Of the 30 patients, 17(56.7%) were males and 13(43.3%) were females. The highest incidence of orbital metastatic disease was among those aged <10 years 9(30%) and >60 years 11(36.7%). Roof was the commonest site of involvement within the orbit 13(43.3%). Proptosis was the main feature at presentation. Diagnosis was made clinically in 14(46.7%) patients and histologically in 16(53.3%). All the 30(100%) cases were referred to the oncology service for further management. Of them, 2(6.7%) patients were lost to follow-up, 20(66.7%) died within one year of diagnosis, and 8 (26.6%) patients were still under treatment.

Conclusions: The diagnosis of orbital metastasis should always be considered for orbital lesions in all age groups, especially in patients with a known cancer elsewhere. Orbital metastasis usually becomes evident at an advanced stage of underlying malignancy, leading to a high mortality rate..

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来源期刊
CiteScore
1.10
自引率
11.10%
发文量
983
审稿时长
3-6 weeks
期刊介绍: Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.
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