{"title":"性细胞形成的关键过程最终可以在体外研究","authors":"Francisco Mendez Diaz, \n Kevin D. Corbett","doi":"10.1038/d41586-025-00305-x","DOIUrl":null,"url":null,"abstract":"The enzyme SPO11 has a crucial role in meiosis, the process that forms sperm and egg cells. The activity of purified SPO11 has now been reconstituted in a cell-free system — enabling the enzyme’s role to be studied in detail. Activity of the purified SPO11 enzyme reconstituted in cell-free system.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"639 8055","pages":"586-587"},"PeriodicalIF":48.5000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Key process in sex-cell formation can finally be studied in vitro\",\"authors\":\"Francisco Mendez Diaz, \\n Kevin D. Corbett\",\"doi\":\"10.1038/d41586-025-00305-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The enzyme SPO11 has a crucial role in meiosis, the process that forms sperm and egg cells. The activity of purified SPO11 has now been reconstituted in a cell-free system — enabling the enzyme’s role to be studied in detail. Activity of the purified SPO11 enzyme reconstituted in cell-free system.\",\"PeriodicalId\":18787,\"journal\":{\"name\":\"Nature\",\"volume\":\"639 8055\",\"pages\":\"586-587\"},\"PeriodicalIF\":48.5000,\"publicationDate\":\"2025-02-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://www.nature.com/articles/d41586-025-00305-x\",\"RegionNum\":1,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature","FirstCategoryId":"103","ListUrlMain":"https://www.nature.com/articles/d41586-025-00305-x","RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Key process in sex-cell formation can finally be studied in vitro
The enzyme SPO11 has a crucial role in meiosis, the process that forms sperm and egg cells. The activity of purified SPO11 has now been reconstituted in a cell-free system — enabling the enzyme’s role to be studied in detail. Activity of the purified SPO11 enzyme reconstituted in cell-free system.
期刊介绍:
Nature is a prestigious international journal that publishes peer-reviewed research in various scientific and technological fields. The selection of articles is based on criteria such as originality, importance, interdisciplinary relevance, timeliness, accessibility, elegance, and surprising conclusions. In addition to showcasing significant scientific advances, Nature delivers rapid, authoritative, insightful news, and interpretation of current and upcoming trends impacting science, scientists, and the broader public. The journal serves a dual purpose: firstly, to promptly share noteworthy scientific advances and foster discussions among scientists, and secondly, to ensure the swift dissemination of scientific results globally, emphasizing their significance for knowledge, culture, and daily life.