儿童食管闭锁/气管食管瘘长期胃肠道并发症的诊断和处理。

IF 4.1 Q1 Medicine Current Gastroenterology Reports Pub Date : 2025-02-25 DOI:10.1007/s11894-025-00968-6
Delia O'Shea, Elle Quinn, William Middlesworth, Julie Khlevner
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引用次数: 0

摘要

回顾目的:食管闭锁/气管食管瘘(EA/TEF)可引起胃肠道(GI)并发症,可始于婴儿期并延伸至成年期。这些疾病的病因通常是多因素的,它们会对喂养、生长、呼吸健康和整体生活质量产生不利影响。这篇综述强调了早期诊断、多学科监测和个性化治疗策略对于有效管理这些并发症和改善受影响儿童的长期预后的重要性。最近的发现:最近的研究集中在以证据为基础的监测方案的发展,以最佳地管理许多观察到的EA/ tef相关的消化并发症。许多并发症源于胃食管运动障碍和EA/TEF固有的机械性梗阻及其手术治疗,包括胃食管反流病、进食困难、吞咽困难、嗜酸性食管炎和误吸引起的肺部后果。EA/TEF患儿消化道并发症的管理需要仔细的、多学科的评估和治疗,包括饮食调整、喂养疗法、药物治疗以及手术和内镜干预。
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Diagnosis and Management of Long-term Gastrointestinal Complications in Pediatric Esophageal Atresia/Tracheoesophageal Fistula.

Purpose of review: Esophageal atresia/tracheoesophageal fistula (EA/TEF) causes gastrointestinal (GI) complications that can begin in infancy and extend into adulthood. The etiology of these is frequently multifactorial, and they can adversely affect feeding, growth, respiratory health, and overall quality of life. This review highlights the importance of early diagnosis, multidisciplinary surveillance, and individualized treatment strategies to effectively manage these complications and improve long-term outcomes for affected children.

Recent findings: Recent studies have focused on the development of evidence-based surveillance protocols to optimally manage the numerous observed EA/TEF-associated digestive complications. Many of these complications stem from the combination of gastroesophageal dysmotility and mechanical obstruction inherent to EA/TEF and its surgical management, and include gastroesophageal reflux disease, feeding difficulties, dysphagia, eosinophilic esophagitis, and pulmonary consequences of aspiration. Management of GI complications in children with EA/TEF requires careful, multidisciplinary evaluation and treatment, incorporating dietary modifications, feeding therapy, pharmacotherapy, and surgical and endoscopic interventions.

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来源期刊
Current Gastroenterology Reports
Current Gastroenterology Reports Medicine-Gastroenterology
CiteScore
7.80
自引率
0.00%
发文量
19
期刊介绍: As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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