使用命名实体识别和快速工程从非英语乳房x光检查报告中自动提取关键实体。

IF 3.7 3区 医学 Q2 ENGINEERING, BIOMEDICAL Bioengineering Pub Date : 2025-02-10 DOI:10.3390/bioengineering12020168
Zafer Akcali, Hazal Selvi Cubuk, Arzu Oguz, Murat Kocak, Aydan Farzaliyeva, Fatih Guven, Mehmet Nezir Ramazanoglu, Efe Hasdemir, Ozden Altundag, Ahmet Muhtesem Agildere
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引用次数: 0

摘要

目的:命名实体识别(NER)为从文本中自动提取关键临床信息提供了一种强大的方法,但目前的模型往往缺乏对非英语语言的足够支持。材料和方法:本研究使用谷歌的Gemini 1.5 Pro研究了基于提示的NER方法,这是一个具有150万个token上下文窗口的大型语言模型(LLM)。我们专注于从土耳其乳房x光检查报告中提取重要的临床实体,这是一种可用的自然语言处理(NLP)工具有限的语言。我们的方法采用多镜头学习,在来自75份初始报告的26,000个令牌提示中纳入165个示例。我们在85份单独的未注释报告中测试了该模型,重点关注五个关键实体:解剖(ANAT)、印象(IMP)、观察存在(OBS-P)、缺失(OBS-A)和不确定性(OBS-U)。结果:我们的方法取得了较高的准确性,松弛匹配的宏观平均F1得分为0.99,精确匹配的宏观平均F1得分为0.84。在宽松匹配中,模型的F1得分为ANAT 0.99, IMP 0.99, OBS-P 1.00, OBS-A 1.00, OBS-U 0.99。对于精确匹配,ANAT的F1评分为0.88,IMP为0.79,OBS-P为0.78,OBS-A为0.94,OBS-U为0.82。讨论:这些结果表明,使用大型语言模型的多镜头提示工程方法为NLP资源不太发达的语言提供了一种有效的自动化临床信息提取方法,并且据文献报道,通常优于零镜头、五镜头和其他少镜头方法。结论:这种方法有可能显著改善多语言医疗环境中的临床工作流程和研究工作。
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Automated Extraction of Key Entities from Non-English Mammography Reports Using Named Entity Recognition with Prompt Engineering.

Objective: Named entity recognition (NER) offers a powerful method for automatically extracting key clinical information from text, but current models often lack sufficient support for non-English languages.

Materials and methods: This study investigated a prompt-based NER approach using Google's Gemini 1.5 Pro, a large language model (LLM) with a 1.5-million-token context window. We focused on extracting important clinical entities from Turkish mammography reports, a language with limited available natural language processing (NLP) tools. Our method employed many-shot learning, incorporating 165 examples within a 26,000-token prompt derived from 75 initial reports. We tested the model on a separate set of 85 unannotated reports, concentrating on five key entities: anatomy (ANAT), impression (IMP), observation presence (OBS-P), absence (OBS-A), and uncertainty (OBS-U).

Results: Our approach achieved high accuracy, with a macro-averaged F1 score of 0.99 for relaxed match and 0.84 for exact match. In relaxed matching, the model achieved F1 scores of 0.99 for ANAT, 0.99 for IMP, 1.00 for OBS-P, 1.00 for OBS-A, and 0.99 for OBS-U. For exact match, the F1 scores were 0.88 for ANAT, 0.79 for IMP, 0.78 for OBS-P, 0.94 for OBS-A, and 0.82 for OBS-U.

Discussion: These results indicate that a many-shot prompt engineering approach with large language models provides an effective way to automate clinical information extraction for languages where NLP resources are less developed, and as reported in the literature, generally outperforms zero-shot, five-shot, and other few-shot methods.

Conclusion: This approach has the potential to significantly improve clinical workflows and research efforts in multilingual healthcare environments.

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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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