Sofiane Habibatni, Jessica Maiuolo, Federica Davì, Zeroual Samir, Bouazza Lyas, Francesco Cacciola, Roberto Laganà Vinci, Luigi Mondello, Maria Fernanda Taviano, Natalizia Miceli
{"title":"大戟叶水醇提取物的酚类特征、抗氧化和神经保护活性的研究。阿尔及利亚的一种野生木蕨。","authors":"Sofiane Habibatni, Jessica Maiuolo, Federica Davì, Zeroual Samir, Bouazza Lyas, Francesco Cacciola, Roberto Laganà Vinci, Luigi Mondello, Maria Fernanda Taviano, Natalizia Miceli","doi":"10.1080/09603123.2025.2461098","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of this research was to investigate the phenolic profile and some biological properties of the leaves of <i>Euphorbia bupleuroides</i> subsp. <i>luteola</i> grown wild in Algeria, still unexplored. The leaves were subjected to extraction with 80% MeOH using simple maceration (SM) and ultrasound-assisted maceration (UM) to establish the most efficient conditions for the recovery of phenolic compounds. The study of antioxidant potential suggested that SM and UM extracts displayed a superimposable activity both in the DPPH test and in the reducing power assay. On the other hand, in the Fe2+ chelating activity assay, SM was more active than UM. SM extract prevented damage induced by β-amyloid protein (Aβ) being more effective against ROS generated after treatment with Aβ. In addition, SM exhibited later protection against malondialdehyde. In conclusion, it is possible to state that simple maceration represents an effective technique for the recovery of compounds with antioxidant and neuroprotective properties from <i>E. bupleuroides</i> subsp. <i>luteola</i> leaves.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"2742-2758"},"PeriodicalIF":1.9000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Characterization of the phenolic profile, antioxidant and neuroprotective activity of leaf hydroalcoholic extracts of <i>Euphorbia bupleuroides</i> subsp. <i>luteola</i> (Kralik) maire growing wild in Algeria.\",\"authors\":\"Sofiane Habibatni, Jessica Maiuolo, Federica Davì, Zeroual Samir, Bouazza Lyas, Francesco Cacciola, Roberto Laganà Vinci, Luigi Mondello, Maria Fernanda Taviano, Natalizia Miceli\",\"doi\":\"10.1080/09603123.2025.2461098\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The objective of this research was to investigate the phenolic profile and some biological properties of the leaves of <i>Euphorbia bupleuroides</i> subsp. <i>luteola</i> grown wild in Algeria, still unexplored. The leaves were subjected to extraction with 80% MeOH using simple maceration (SM) and ultrasound-assisted maceration (UM) to establish the most efficient conditions for the recovery of phenolic compounds. The study of antioxidant potential suggested that SM and UM extracts displayed a superimposable activity both in the DPPH test and in the reducing power assay. On the other hand, in the Fe2+ chelating activity assay, SM was more active than UM. SM extract prevented damage induced by β-amyloid protein (Aβ) being more effective against ROS generated after treatment with Aβ. In addition, SM exhibited later protection against malondialdehyde. In conclusion, it is possible to state that simple maceration represents an effective technique for the recovery of compounds with antioxidant and neuroprotective properties from <i>E. bupleuroides</i> subsp. <i>luteola</i> leaves.</p>\",\"PeriodicalId\":14039,\"journal\":{\"name\":\"International Journal of Environmental Health Research\",\"volume\":\" \",\"pages\":\"2742-2758\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Environmental Health Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/09603123.2025.2461098\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Environmental Health Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09603123.2025.2461098","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/26 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
Characterization of the phenolic profile, antioxidant and neuroprotective activity of leaf hydroalcoholic extracts of Euphorbia bupleuroides subsp. luteola (Kralik) maire growing wild in Algeria.
The objective of this research was to investigate the phenolic profile and some biological properties of the leaves of Euphorbia bupleuroides subsp. luteola grown wild in Algeria, still unexplored. The leaves were subjected to extraction with 80% MeOH using simple maceration (SM) and ultrasound-assisted maceration (UM) to establish the most efficient conditions for the recovery of phenolic compounds. The study of antioxidant potential suggested that SM and UM extracts displayed a superimposable activity both in the DPPH test and in the reducing power assay. On the other hand, in the Fe2+ chelating activity assay, SM was more active than UM. SM extract prevented damage induced by β-amyloid protein (Aβ) being more effective against ROS generated after treatment with Aβ. In addition, SM exhibited later protection against malondialdehyde. In conclusion, it is possible to state that simple maceration represents an effective technique for the recovery of compounds with antioxidant and neuroprotective properties from E. bupleuroides subsp. luteola leaves.
期刊介绍：
International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.
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