在低资源环境中设计全国快速疫苗覆盖率调查:刚果民主共和国的经验 2018-2023

IF 3.4 3区 医学 Q2 IMMUNOLOGY Vaccine Pub Date : 2025-04-19 Epub Date: 2025-03-02 DOI:10.1016/j.vaccine.2025.126956
Eric M. Mafuta , Aimée M. Lulebo , Jean-Bosco N. Kasonga , Nono M. Mvuama , Christophe L. Luhata , Nicole A. Hoff , Dalau M. Nkamba , Sydney Merritt , John Samuel Otomba , Branly K. Mbunga , Aimé M.W.B. Cikomola , Anne W. Rimoin , Jean-Crispin Mukendi , Jean Bernard LeGargasson , Cyril Nogier , Léon Kinuani , Marcellin Mengouo Nimpa , Daniel K. Ishoso , Adèle N. Mudipanu , Deo Manirakiza , Paul-Samson D. Lusamba
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引用次数: 0

摘要

在刚果民主共和国,疫苗覆盖率的估算传统上依赖于大规模调查,如人口与健康调查(DHS)和多指标类集调查(MICS)。然而,这些调查不频繁,成本高,并且缺乏卫生区或区(HZ)级别决策所需的粒度。本文描述了金沙萨公共卫生学院(KSPH)和技术合作伙伴根据世界卫生组织(WHO)指南进行的疫苗覆盖率调查(KSPH VCS)的发展,其目的是在HZ水平上提供及时、具有成本效益和代表性的VC估计。KSPH VCS采用横截面设计和多阶段抽样方法在HZ水平上对家庭进行抽样。尽管有普查区,但仍将保健区作为集群,并将资格年龄范围从12 -23个月扩大到6-23个月。每个HZ的样本量是根据MICS-2018提供的疫苗覆盖率计算的。它整合了对疫苗接种障碍和促进因素的评估。自2023年以来,它已纳入疟疾指标。自2018年启动以来,该计划已扩展到全国,到2022年将覆盖刚果民主共和国的所有26个省份。KSPH VCS的调查结果提供了HZ水平的估计,可以与省和国家的估计相结合。结果有助于评估国家免疫战略,包括Mashako计划,并为总统免疫论坛提供信息。它们为国家和省级的资源分配、业务规划和政策决策提供了信息,因为它们为HZ级别的业务决策提供了所需的粒度。其结果还有助于全球免疫估计,包括世卫组织/儿童基金会国家免疫覆盖率估计。KSPH VCS证明了在低资源环境下由当地主导、具有成本效益和适应性的VCS调查的可行性。它的成功突出了在其他寻求改善免疫监测和卫生系统绩效的低收入和中等收入国家实施类似方法的潜力。
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Designing a National Rapid Vaccine Coverage Survey in low-resource settings: Experiences from the Democratic Republic of the Congo 2018–2023
In the Democratic Republic of the Congo (DRC), estimating vaccine coverage (VC) has traditionally relied on large-scale surveys such as the Demographic and Health Surveys (DHS) and the Multiple Indicator Cluster Surveys (MICS). However, these surveys are infrequent, costly, and lack the granularity needed for decision-making at the health district or zone (HZ) level. This paper describes the development by the Kinshasa School of Public Health (KSPH), and technical partners of a Vaccine Coverage Survey (KSPH VCS), adapted from the World Health Organization (WHO) guidelines, which aims to provides timely, cost-effective, and representative estimates of VC at the HZ level.
The KSPH VCS adopted a cross-sectional design and a multi-stage sampling approach to sample households at the HZ level. It uses Health Area as cluster in spite of Enumeration Area, and extends the eligibility age range from 12 -23 months to 6–23 months. The sample size for each HZ was calculated using vaccine coverage provided in MICS-2018. It integrates assessments of barriers and enablers to vaccination. Since 2023, it has included malaria indicators. Since its inception in 2018, it has expanded nationwide, covering all 26 provinces of the DRC by 2022.
Findings from the KSPH VCS provides estimates at the HZ level that could be combined to provincial and national estimates. Results have been instrumental in evaluating national immunization strategies, including the Mashako Plan and informing Presidential Forums on immunization. They have informed resource allocation, operational planning, and policy decisions at both national and provincial levels as they provided granularity needed for operational decision-making at the HZ level. Its results have also contributed to global immunization estimates, including the WHO/UNICEF Estimates of National Immunization Coverage (WUENIC).
The KSPH VCS demonstrates the feasibility of a locally led, cost-effective, and adaptable VC survey in a low-resource setting. Its success highlights the potential for similar methodologies to be implemented in other low- and middle-income countries seeking to improve immunization monitoring and health system performance.
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来源期刊
Vaccine
Vaccine 医学-免疫学
CiteScore
8.70
自引率
5.50%
发文量
992
审稿时长
131 days
期刊介绍: Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.
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