Xinying Gong , Yulu Tian , Yuanjun Tong , Yibin Yuan , Shiyu Peng , Dongmei Wang , Hongqun Tao , Qinwen Tan , Zhengjun Gong
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Therefore, an effective strategy for adjusting pore size in LMOFs is essential to enhance the sensitivity and selectivity of fluorescence recognition.</div></div><div><h3>Results</h3><div>In this study, a fluorescence probe NH<sub>2</sub>-UiO-66@cur was synthesized, where curcumin was utilized to modulate the pore size of NH<sub>2</sub>-UiO-66, resulting in a fluorescence “turn-on” response for the rapid detection of monocrotophos (MCP). The incorporation of curcumin increased the average pore size of NH<sub>2</sub>-UiO-66 from 2.01 to 3.61 nm, thereby facilitating the mass transfer of MCP in NH<sub>2</sub>-UiO-66@cur. Additionally, the coordinating of MCP with the zirconium node effectively block the ligand-to-metal charge transfer (LMCT) process, significantly improving sensitivity with an ultra-low detection limit of 0.41 μg L<sup>−1</sup> for MCP. The NH<sub>2</sub>-UiO-66@cur sensor exhibited excellent selectivity for MCP compared to other organosphosphorus compounds, as well as robust interference resistance. In practical applications, the fluorescence probe showed stable and accurate detection potential, with spiking recoveries ranging from 84.2 % to 105 % in environmental water samples.</div></div><div><h3>Significance</h3><div>This work provides a novel strategy for tailoring the pore size for a MOF sensor platform, which notably enhances the mass transfer and fluorescence emission intensity by blocking LMCT effect. As a result, it improves the detection sensitivity and selectivity on trace organophosphate pollutants in the environment samples, addressing critical concerns in environmental monitoring.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343915"},"PeriodicalIF":6.1000,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rapid detection of organophosphorus pesticide monocrotophos by pore size-regulated amplified fluorescence “turn-on” response of Zr-MOF\",\"authors\":\"Xinying Gong , Yulu Tian , Yuanjun Tong , Yibin Yuan , Shiyu Peng , Dongmei Wang , Hongqun Tao , Qinwen Tan , Zhengjun Gong\",\"doi\":\"10.1016/j.aca.2025.343915\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Organophosphorus pesticides pose a severe threat to human health even at trace levels in the environment, owing to their high persistence and neurotoxic effects. Rapid detection methods based on luminescent metal organic frameworks (LMOFs) have great advantages in environmental applications, attributing to their unique luminescence characteristics, structural flexibility, high porosity, and tunable synthesis. Therefore, an effective strategy for adjusting pore size in LMOFs is essential to enhance the sensitivity and selectivity of fluorescence recognition.</div></div><div><h3>Results</h3><div>In this study, a fluorescence probe NH<sub>2</sub>-UiO-66@cur was synthesized, where curcumin was utilized to modulate the pore size of NH<sub>2</sub>-UiO-66, resulting in a fluorescence “turn-on” response for the rapid detection of monocrotophos (MCP). The incorporation of curcumin increased the average pore size of NH<sub>2</sub>-UiO-66 from 2.01 to 3.61 nm, thereby facilitating the mass transfer of MCP in NH<sub>2</sub>-UiO-66@cur. Additionally, the coordinating of MCP with the zirconium node effectively block the ligand-to-metal charge transfer (LMCT) process, significantly improving sensitivity with an ultra-low detection limit of 0.41 μg L<sup>−1</sup> for MCP. The NH<sub>2</sub>-UiO-66@cur sensor exhibited excellent selectivity for MCP compared to other organosphosphorus compounds, as well as robust interference resistance. In practical applications, the fluorescence probe showed stable and accurate detection potential, with spiking recoveries ranging from 84.2 % to 105 % in environmental water samples.</div></div><div><h3>Significance</h3><div>This work provides a novel strategy for tailoring the pore size for a MOF sensor platform, which notably enhances the mass transfer and fluorescence emission intensity by blocking LMCT effect. As a result, it improves the detection sensitivity and selectivity on trace organophosphate pollutants in the environment samples, addressing critical concerns in environmental monitoring.</div></div>\",\"PeriodicalId\":240,\"journal\":{\"name\":\"Analytica Chimica Acta\",\"volume\":\"1352 \",\"pages\":\"Article 343915\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2025-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytica Chimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0003267025003095\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytica Chimica Acta","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0003267025003095","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/7 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Rapid detection of organophosphorus pesticide monocrotophos by pore size-regulated amplified fluorescence “turn-on” response of Zr-MOF
Background
Organophosphorus pesticides pose a severe threat to human health even at trace levels in the environment, owing to their high persistence and neurotoxic effects. Rapid detection methods based on luminescent metal organic frameworks (LMOFs) have great advantages in environmental applications, attributing to their unique luminescence characteristics, structural flexibility, high porosity, and tunable synthesis. Therefore, an effective strategy for adjusting pore size in LMOFs is essential to enhance the sensitivity and selectivity of fluorescence recognition.
Results
In this study, a fluorescence probe NH2-UiO-66@cur was synthesized, where curcumin was utilized to modulate the pore size of NH2-UiO-66, resulting in a fluorescence “turn-on” response for the rapid detection of monocrotophos (MCP). The incorporation of curcumin increased the average pore size of NH2-UiO-66 from 2.01 to 3.61 nm, thereby facilitating the mass transfer of MCP in NH2-UiO-66@cur. Additionally, the coordinating of MCP with the zirconium node effectively block the ligand-to-metal charge transfer (LMCT) process, significantly improving sensitivity with an ultra-low detection limit of 0.41 μg L−1 for MCP. The NH2-UiO-66@cur sensor exhibited excellent selectivity for MCP compared to other organosphosphorus compounds, as well as robust interference resistance. In practical applications, the fluorescence probe showed stable and accurate detection potential, with spiking recoveries ranging from 84.2 % to 105 % in environmental water samples.
Significance
This work provides a novel strategy for tailoring the pore size for a MOF sensor platform, which notably enhances the mass transfer and fluorescence emission intensity by blocking LMCT effect. As a result, it improves the detection sensitivity and selectivity on trace organophosphate pollutants in the environment samples, addressing critical concerns in environmental monitoring.
期刊介绍：
Analytica Chimica Acta has an open access mirror journal Analytica Chimica Acta: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Analytica Chimica Acta provides a forum for the rapid publication of original research, and critical, comprehensive reviews dealing with all aspects of fundamental and applied modern analytical chemistry. The journal welcomes the submission of research papers which report studies concerning the development of new and significant analytical methodologies. In determining the suitability of submitted articles for publication, particular scrutiny will be placed on the degree of novelty and impact of the research and the extent to which it adds to the existing body of knowledge in analytical chemistry.
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