{"title":"一种T细胞亚型阻碍损伤后老年脊髓的组织修复。","authors":"Chengle Zhang, Kai Liu","doi":"10.1016/j.neuron.2025.02.011","DOIUrl":null,"url":null,"abstract":"<p><p>In this issue of Neuron, Kong et al.<sup>1</sup> identify targetable natural killer-like T cells that seed the intact aged human and murine spinal cords and increase further after injury. These cells impede myeloid-cell-dependent wound healing in the aged injured cord through expressing natural killer cell granule protein 7 (NKG7).</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 5","pages":"643-645"},"PeriodicalIF":15.0000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A subtype of T cells impedes tissue repair in aged spinal cord after injury.\",\"authors\":\"Chengle Zhang, Kai Liu\",\"doi\":\"10.1016/j.neuron.2025.02.011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In this issue of Neuron, Kong et al.<sup>1</sup> identify targetable natural killer-like T cells that seed the intact aged human and murine spinal cords and increase further after injury. These cells impede myeloid-cell-dependent wound healing in the aged injured cord through expressing natural killer cell granule protein 7 (NKG7).</p>\",\"PeriodicalId\":19313,\"journal\":{\"name\":\"Neuron\",\"volume\":\"113 5\",\"pages\":\"643-645\"},\"PeriodicalIF\":15.0000,\"publicationDate\":\"2025-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuron\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.neuron.2025.02.011\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.02.011","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
A subtype of T cells impedes tissue repair in aged spinal cord after injury.
In this issue of Neuron, Kong et al.1 identify targetable natural killer-like T cells that seed the intact aged human and murine spinal cords and increase further after injury. These cells impede myeloid-cell-dependent wound healing in the aged injured cord through expressing natural killer cell granule protein 7 (NKG7).
期刊介绍：
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.
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