对抗直觉:肠-脑-肺神经免疫回路。

IF 16.9 1区 医学 Q1 NEUROSCIENCES Neuron Pub Date : 2025-03-05 DOI:10.1016/j.neuron.2025.01.029
Brian S Kim
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引用次数: 0

摘要

在这一期的Neuron杂志上,Chen等人发现了一个餐后神经免疫轴,通过这个轴,喂食诱导的胃肠道刺激触发了肺部的2型免疫这项研究暗示,可能存在不同的感觉和运动回路,由大脑在不同组织之间协调,以驱动神经炎症。
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Fighting off a gut feeling: A gut-brain-lung neuroimmune circuit.

In this issue of Neuron, Chen et al. identify a postprandial neuroimmune axis by which feeding-induced stimulation of the gastrointestinal tract triggers type 2 immunity in the lung.1 This study hints that there are likely distinct sensory and motor circuits coordinated by the brain across different tissues to drive neuroinflammation.

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来源期刊
Neuron
Neuron 医学-神经科学
CiteScore
24.50
自引率
3.10%
发文量
382
审稿时长
1 months
期刊介绍: Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.
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