Vishnuvarthan Ganapathy, Anitha Balaji, T S Sampath Kumar, Mohanasatheesh Shanmugam
{"title":"使用CBCT评估蛋壳衍生的纳米羟基磷灰石作为骨内缺损的骨移植物-一项随机对照试验。","authors":"Vishnuvarthan Ganapathy, Anitha Balaji, T S Sampath Kumar, Mohanasatheesh Shanmugam","doi":"10.4103/jpbs.jpbs_1041_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The study aims to assess the effectiveness of eggshell-derived nanohydroxyapatite (EnHA) as a bone graft material for treating intrabony defects, using cone-beam computed tomography (CBCT) for evaluation.</p><p><strong>Materials and methods: </strong>Ten patients were divided into two groups: Group 1: individuals with 2-wall defects, Group 2: those with 3-wall defects. Follow-up appointments at 1-, 3-, and 6-month intervals included assessments of clinical attachment level (CAL), probing depth (PD), and gingival recession (GR). CBCT scans were conducted pre-operative, immediately post-surgery, and at 1-month, 3-month, and 5-month follow-ups.</p><p><strong>Results: </strong>In both groups, clinical parameters such as CAL, PD, and CBCT measurements reveal significant decreases in CAL and PD values alongside positive trends in CBCT measurements. Additionally, Group 2 exhibited enhancements in periodontal health, suggesting the potential effectiveness of EnHA.</p><p><strong>Conclusion: </strong>EnHA demonstrates potential as a substitute for bone grafting in intrabony defects, showing favourable trends in both clinical and CBCT evaluations during a 6-month observation period.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"16 Suppl 5","pages":"S4517-S4521"},"PeriodicalIF":0.9000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888653/pdf/","citationCount":"0","resultStr":"{\"title\":\"Eggshell Derived Nanohydroxyapatite as a Bone Graft for Intrabony Defects was Evaluated Using (CBCT) - A Randomized Controlled Trial.\",\"authors\":\"Vishnuvarthan Ganapathy, Anitha Balaji, T S Sampath Kumar, Mohanasatheesh Shanmugam\",\"doi\":\"10.4103/jpbs.jpbs_1041_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>The study aims to assess the effectiveness of eggshell-derived nanohydroxyapatite (EnHA) as a bone graft material for treating intrabony defects, using cone-beam computed tomography (CBCT) for evaluation.</p><p><strong>Materials and methods: </strong>Ten patients were divided into two groups: Group 1: individuals with 2-wall defects, Group 2: those with 3-wall defects. Follow-up appointments at 1-, 3-, and 6-month intervals included assessments of clinical attachment level (CAL), probing depth (PD), and gingival recession (GR). CBCT scans were conducted pre-operative, immediately post-surgery, and at 1-month, 3-month, and 5-month follow-ups.</p><p><strong>Results: </strong>In both groups, clinical parameters such as CAL, PD, and CBCT measurements reveal significant decreases in CAL and PD values alongside positive trends in CBCT measurements. Additionally, Group 2 exhibited enhancements in periodontal health, suggesting the potential effectiveness of EnHA.</p><p><strong>Conclusion: </strong>EnHA demonstrates potential as a substitute for bone grafting in intrabony defects, showing favourable trends in both clinical and CBCT evaluations during a 6-month observation period.</p>\",\"PeriodicalId\":94339,\"journal\":{\"name\":\"Journal of pharmacy & bioallied sciences\",\"volume\":\"16 Suppl 5\",\"pages\":\"S4517-S4521\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888653/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of pharmacy & bioallied sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jpbs.jpbs_1041_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of pharmacy & bioallied sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jpbs.jpbs_1041_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/30 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Eggshell Derived Nanohydroxyapatite as a Bone Graft for Intrabony Defects was Evaluated Using (CBCT) - A Randomized Controlled Trial.
Aim: The study aims to assess the effectiveness of eggshell-derived nanohydroxyapatite (EnHA) as a bone graft material for treating intrabony defects, using cone-beam computed tomography (CBCT) for evaluation.
Materials and methods: Ten patients were divided into two groups: Group 1: individuals with 2-wall defects, Group 2: those with 3-wall defects. Follow-up appointments at 1-, 3-, and 6-month intervals included assessments of clinical attachment level (CAL), probing depth (PD), and gingival recession (GR). CBCT scans were conducted pre-operative, immediately post-surgery, and at 1-month, 3-month, and 5-month follow-ups.
Results: In both groups, clinical parameters such as CAL, PD, and CBCT measurements reveal significant decreases in CAL and PD values alongside positive trends in CBCT measurements. Additionally, Group 2 exhibited enhancements in periodontal health, suggesting the potential effectiveness of EnHA.
Conclusion: EnHA demonstrates potential as a substitute for bone grafting in intrabony defects, showing favourable trends in both clinical and CBCT evaluations during a 6-month observation period.