胫骨近端痤疮表皮杆菌Brodie脓肿1例

Medical Reports Pub Date : 2025-06-01 Epub Date: 2025-03-10 DOI:10.1016/j.hmedic.2025.100184
Zeina Morcos , Chloe Lahoud , Salman Khan , Gabrielle Dabrowski , Allison Glaser
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摘要

布罗迪脓肿是一种亚急性骨髓炎,其特征是骨内明显的脓性聚集。它表现为非特异性体征和症状。诊断布罗迪脓肿通常需要核磁共振成像,这比传统的x射线要好。它可能被误认为是骨样骨瘤、朗格汉斯细胞组织细胞增多症、软骨肉瘤、嗜酸性肉芽肿或肺结核。金黄色葡萄球菌是最常见的细菌。病例介绍:我们报告一例独特的布罗迪脓肿发生在胫骨近端,继发于痤疮表皮杆菌,这是一种罕见的布罗迪脓肿的病原体,在以前的右胫骨干骨折外固定支架合并针位路感染多年后。由于与正常皮肤菌群相关,传统上认为痤疮是一种非致病性污染物,但由于培养基不足和临床症状不明显,在其他感染中,痤疮常被误诊和漏报。布罗迪脓肿的治疗通常包括手术清创,然后使用抗生素,尽管最佳的抗生素治疗方案尚不清楚。结论对于本例的非典型表现,尚需进一步研究。
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Cutibacterium acnes Brodie's abscess of the proximal tibia: A case report

Introduction

Brodie’s abscess, a subacute osteomyelitis, is characterized by a well-demarcated collection of purulence within the bone. It presents with nonspecific signs and symptoms. Diagnosing Brodie's abscess typically involves MRI, which is superior to conventional X-rays. It can be mistaken for osteoid osteoma, Langerhans cell histiocytosis, chondrosarcoma, eosinophilic granuloma, or tuberculosis. Staphylococcus aureus is the most common organism involved.

Case Presentation

We present a unique case of Brodie’s abscess within the proximal tibia secondary to Cutibacterium acnes, an unusual pathogen in Brodie’s Abscess, in a setting of previous right tibial shaft fracture with external fixation complicated by pin-site tract infection after many years.

Discussion

Traditionally viewed as a nonpathogenic contaminant due to its association with normal skin flora, C. acnes is often underdiagnosed and underreported in other infections due to inadequate culture media and subtle clinical symptoms. Treatment of Brodie’s abscess generally involves surgical debridement followed by antibiotics, though the optimal antibiotic regimen is unclear.

Conclusion

Further research is needed regarding atypical presentations of C. acnes such as our case.
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