干纺丝聚己二酸丁二酯(PBAT)纤维制备的可生物降解抗菌纱布。

IF 4.1 3区 化学 Q2 POLYMER SCIENCE Macromolecular Rapid Communications Pub Date : 2025-03-11 DOI:10.1002/marc.202401066
Qian Wang, Yue Cao, Zongxu Na, Jing Li, Li Yu, Zhaoyuan Li, Yanzhe Ding, Bo Lu
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引用次数: 0

摘要

可生物降解抗菌纱布是一种环保医用敷料,对伤口的保护和愈合起着至关重要的作用。聚己二酸丁二烯对苯二甲酸酯(PBAT)由于其卓越的生物可降解性、生物相容性、可加工性和灵活性,为开发可生物降解的抗菌纱布提供了一个有前途的平台。迄今为止,大多数工作都集中在利用静电纺丝制备PBAT抗菌纱布上。PBAT抗菌纱布的抗拉强度和断裂伸长率不理想,限制了其实际应用。此外,静电纺丝技术设备成本高,生产效率相对较低,不适合大规模生产。本文报道了一种干法纺丝技术,可以大规模、高效率地生产出具有优异力学性能(抗拉强度14 MPa,断裂伸长率1600%)的PBAT纤维(151 m·min-1)。抗菌纱是将市售和使用过的抗菌剂单宁酸(TA)加入传统针织工艺制备的PBAT纤维织物表面而制成的。抗菌实验结果表明,所研制的抗菌纱布对引起伤口感染的常见病原菌金黄色葡萄球菌(S. aureus)和大肠杆菌(E. coli)的生长有明显的抑制作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Biodegradable Antimicrobial Gauzes Enabled by Dry Spinning Poly(Butylene Adipate Terephthalate) (PBAT) Fibers

Biodegradable antimicrobial gauzes are environmentally friendly medical dressings taking essential role in the protection and healing of wounds. Poly (butylene adipate terephthalate) (PBAT) offers a promising platform for exploiting biodegradable antimicrobial gauzes attributed to its exceptional biodegradability, biocompatibility, processability, and flexibility. To date, most work is focused on utilizing electrostatic spinning to fabricate PBAT antimicrobial gauzes. The PBAT antimicrobial gauzes exhibit unsatisfactory tensile strength and breaking elongation restricting their practical application. Moreover, electrostatic spinning technology requires high-cost equipment and presents relatively lower production efficiency which is not suitable for large-scale production. Herein, a dry spinning technology is reported that can manufacture PBAT fibers with superb mechanical properties (tensile strength 14 MPa, breaking elongation 1600%) in large-scale and high-efficiency (151 m·min−1). The antimicrobial gauzes are achieved by loading commercially available and used antibacterial agent, tannic acid (TA), to the surface of the textiles prepared from the PBAT fibers by the traditional knitting process. The antibacterial result demonstrates that the developed antimicrobial gauzes display a remarkable inhibitory effect on the growth the Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) which are common bacteria that cause wound infections.

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来源期刊
Macromolecular Rapid Communications
Macromolecular Rapid Communications 工程技术-高分子科学
CiteScore
7.70
自引率
6.50%
发文量
477
审稿时长
1.4 months
期刊介绍: Macromolecular Rapid Communications publishes original research in polymer science, ranging from chemistry and physics of polymers to polymers in materials science and life sciences.
期刊最新文献
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