内脏战胜思想:探索强大的内脏-大脑轴。

IF 5.8 2区 医学 Q1 NUTRITION & DIETETICS Nutrients Pub Date : 2025-02-28 DOI:10.3390/nu17050842
Stefana-Maria Petrut, Alexandra Maria Bragaru, Alice Elena Munteanu, Adina-Diana Moldovan, Cosmin-Alec Moldovan, Elena Rusu
{"title":"内脏战胜思想:探索强大的内脏-大脑轴。","authors":"Stefana-Maria Petrut, Alexandra Maria Bragaru, Alice Elena Munteanu, Adina-Diana Moldovan, Cosmin-Alec Moldovan, Elena Rusu","doi":"10.3390/nu17050842","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> The human gastrointestinal tract is home to a wide variety of microorganisms. For some decades now, bacteria known as probiotics have been added to various foods because of their beneficial effects for human health. Evidence indicates that probiotics significantly regulate gut microbiota, which is vital for digestion, metabolism, immune function, and mental health. <b>Methods:</b> We conducted a narrative review of available original research published in PubMed for the past ten years focusing on recent advancements that provide a thorough understanding of the relationship between the gastrointestinal system and the brain. <b>Results:</b> Recent advances in research have focused on the importance of gut microbiota in influencing mental health. The microbiota-gut-brain axis is a complex, bidirectional communication network linking the central nervous system and the gastrointestinal tract, which highlights how the gut and brain are deeply interconnected and influence each other in ways that affect our overall health, emotions, and behavior. This powerful link is a major area of research as scientists discover more about how gut health can impact mental well-being. <b>Conclusions:</b> A comprehensive understanding of microbiota composition and mechanisms involved in these interactions between the gut and the brain could shape future medical and therapeutic approaches. It would balance scientific explanation with clinical relevance, offering insights into how understanding the brain-gut axis can revolutionize our approach to treating mental health and gastrointestinal disorders.</p>","PeriodicalId":19486,"journal":{"name":"Nutrients","volume":"17 5","pages":""},"PeriodicalIF":5.8000,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901622/pdf/","citationCount":"0","resultStr":"{\"title\":\"Gut over Mind: Exploring the Powerful Gut-Brain Axis.\",\"authors\":\"Stefana-Maria Petrut, Alexandra Maria Bragaru, Alice Elena Munteanu, Adina-Diana Moldovan, Cosmin-Alec Moldovan, Elena Rusu\",\"doi\":\"10.3390/nu17050842\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Background:</b> The human gastrointestinal tract is home to a wide variety of microorganisms. For some decades now, bacteria known as probiotics have been added to various foods because of their beneficial effects for human health. Evidence indicates that probiotics significantly regulate gut microbiota, which is vital for digestion, metabolism, immune function, and mental health. <b>Methods:</b> We conducted a narrative review of available original research published in PubMed for the past ten years focusing on recent advancements that provide a thorough understanding of the relationship between the gastrointestinal system and the brain. <b>Results:</b> Recent advances in research have focused on the importance of gut microbiota in influencing mental health. The microbiota-gut-brain axis is a complex, bidirectional communication network linking the central nervous system and the gastrointestinal tract, which highlights how the gut and brain are deeply interconnected and influence each other in ways that affect our overall health, emotions, and behavior. This powerful link is a major area of research as scientists discover more about how gut health can impact mental well-being. <b>Conclusions:</b> A comprehensive understanding of microbiota composition and mechanisms involved in these interactions between the gut and the brain could shape future medical and therapeutic approaches. It would balance scientific explanation with clinical relevance, offering insights into how understanding the brain-gut axis can revolutionize our approach to treating mental health and gastrointestinal disorders.</p>\",\"PeriodicalId\":19486,\"journal\":{\"name\":\"Nutrients\",\"volume\":\"17 5\",\"pages\":\"\"},\"PeriodicalIF\":5.8000,\"publicationDate\":\"2025-02-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11901622/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrients\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/nu17050842\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrients","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/nu17050842","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0

摘要

背景:人类胃肠道是多种微生物的家园。几十年来,被称为益生菌的细菌被添加到各种食物中,因为它们对人体健康有益。有证据表明,益生菌可以显著调节肠道菌群,这对消化、代谢、免疫功能和心理健康至关重要。方法:我们对过去十年发表在PubMed上的现有原始研究进行了叙述性回顾,重点关注最近的进展,这些进展提供了对胃肠道系统和大脑之间关系的全面理解。结果:最近的研究进展集中在肠道微生物群在影响心理健康方面的重要性。微生物-肠道-大脑轴是连接中枢神经系统和胃肠道的一个复杂的双向通信网络,它突出了肠道和大脑是如何紧密相连的,并以影响我们整体健康、情绪和行为的方式相互影响。随着科学家们越来越多地发现肠道健康如何影响心理健康,这种强有力的联系是一个主要的研究领域。结论:全面了解肠道和大脑之间这些相互作用中涉及的微生物群组成和机制可以塑造未来的医学和治疗方法。它将平衡科学解释与临床相关性,为理解脑肠轴如何彻底改变我们治疗精神健康和胃肠道疾病的方法提供见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Gut over Mind: Exploring the Powerful Gut-Brain Axis.

Background: The human gastrointestinal tract is home to a wide variety of microorganisms. For some decades now, bacteria known as probiotics have been added to various foods because of their beneficial effects for human health. Evidence indicates that probiotics significantly regulate gut microbiota, which is vital for digestion, metabolism, immune function, and mental health. Methods: We conducted a narrative review of available original research published in PubMed for the past ten years focusing on recent advancements that provide a thorough understanding of the relationship between the gastrointestinal system and the brain. Results: Recent advances in research have focused on the importance of gut microbiota in influencing mental health. The microbiota-gut-brain axis is a complex, bidirectional communication network linking the central nervous system and the gastrointestinal tract, which highlights how the gut and brain are deeply interconnected and influence each other in ways that affect our overall health, emotions, and behavior. This powerful link is a major area of research as scientists discover more about how gut health can impact mental well-being. Conclusions: A comprehensive understanding of microbiota composition and mechanisms involved in these interactions between the gut and the brain could shape future medical and therapeutic approaches. It would balance scientific explanation with clinical relevance, offering insights into how understanding the brain-gut axis can revolutionize our approach to treating mental health and gastrointestinal disorders.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nutrients
Nutrients NUTRITION & DIETETICS-
CiteScore
9.20
自引率
15.30%
发文量
4599
审稿时长
16.74 days
期刊介绍: Nutrients (ISSN 2072-6643) is an international, peer-reviewed open access advanced forum for studies related to Human Nutrition. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
期刊最新文献
Nutritional and Metabolic Health Profiling in a Large Clinic-Based Sample of Mexican Adults: A Cross-Sectional Study. Curcumin Induces Pyroptosis-Associated Molecular Changes in Osteosarcoma Cells Correlating with the ROS/NLRP3/CASPASE-1/GSDMD Axis with Concomitant PI3K/AKT Suppression and Apoptosis Activation. 1,5-Anhydro-D-Mannitol Is a Potentially Low-Energy Carbohydrate: A Dual-Model Approach in Rats and a Randomized, Three-Way Crossover Trial in Humans. Adherence to the DASH Diet in the Spanish Population and Its Environmental Impact: An Ecological Study. Impact of Vitamin D Concentration on Postoperative Outcomes and Complications Following Total Knee Arthroplasty: A Scoping Review of the Literature.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1