Keyuan Xu , Jia Chen , Hongyu Luo , Shuangyun Liu , Shaobo Ni , Xinkun Shen , Yilong Dong , Xiaoyi Pan
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引用次数: 0
摘要
研究人员采用浸泡法将不同形态的磷酸钙（CaP）涂层涂覆到钛的表面，并在氧化应激（OS）条件下考察了其抗炎和增强骨质的特性。实验结果表明，与纯钛相比，羟基磷灰石处理过的钛具有更强的抗氧化能力。这种改善通过有效调节骨免疫微环境，支持 MC3T3-E1 细胞的附着、生长和成骨分化。同时，在不同 pH 值条件下形成的 CaP 涂层显示出显著差异，与 Ti-HAp 相比，Ti-HAs 表现出更优越的性能，尤其是在 OS 条件下。
Evaluation of the bone-enhancing potential of calcium phosphate coatings with different morphologies on titanium surfaces under oxidative stress conditions
Calcium phosphate (CaP) coatings with varying morphologies were applied to the surface of titanium using an immersion method, and their anti-inflammatory and bone-enhancing properties were examined under oxidative stress (OS) conditions. The experimental results demonstrated that hydroxyapatite-treated titanium exhibits superior antioxidant capabilities compared to pure titanium. This improvement supports cell attachment, growth, and osteogenic differentiation of MC3T3-E1 cells by efficiently modulating the bone immune microenvironment. Meanwhile, the CaP coatings formed under different pH conditions show significant differences, with Ti–HAs demonstrating superior performance compared to Ti-HAp, especially under OS conditions.
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Materials Chemistry and Physics is devoted to short communications, full-length research papers and feature articles on interrelationships among structure, properties, processing and performance of materials. The Editors welcome manuscripts on thin films, surface and interface science, materials degradation and reliability, metallurgy, semiconductors and optoelectronic materials, fine ceramics, magnetics, superconductors, specialty polymers, nano-materials and composite materials.
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