封面专题:基于硒糖、类固醇和富勒烯的有机嵌合体作为β淀粉样肽聚合的潜在抑制剂(ChemPlusChem 3/2025)

IF 3.1 4区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY ChemPlusChem Pub Date : 2025-03-17 DOI:10.1002/cplu.202580302
Reinier Lemos, Yoana Pérez-Badell, Mauro De Nisco, Andrea Carpentieri, Margarita Suárez, Silvana Pedatella
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引用次数: 0

摘要

覆盖特征表明杂化甲烷富勒烯与β-淀粉样肽(Aβ)聚集体相互作用。理论计算表明,富勒烯、硒糖和类固醇这三种特殊结构的结合,使这些杂交分子成为Aβ肽聚集的潜在抑制剂。更多细节可以在Margarita Suárez, Silvana Pedatella和同事的研究文章中找到(DOI: 10.1002/ cpls .202400404)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Cover Feature: Organic Chimeras Based on Selenosugars, Steroids, and Fullerenes as Potential Inhibitors of the β-amyloid Peptide Aggregation (ChemPlusChem 3/2025)

The cover feature shows the interaction of hybrid methanofullerenes with β-amyloid peptide (Aβ) aggregates. The combination of three privileged structures, fullerenes, selenosugars, and steroids, makes these hybrid molecules potential inhibitors of Aβ peptide aggregation, as theoretical calculations suggest. More details can be found in the Research Article by Margarita Suárez, Silvana Pedatella, and co-workers (DOI: 10.1002/cplu.202400404).

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来源期刊
ChemPlusChem
ChemPlusChem CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
5.90
自引率
0.00%
发文量
200
审稿时长
1 months
期刊介绍: ChemPlusChem is a peer-reviewed, general chemistry journal that brings readers the very best in multidisciplinary research centering on chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. Fully comprehensive in its scope, ChemPlusChem publishes articles covering new results from at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem). All suitable submissions undergo balanced peer review by experts in the field to ensure the highest quality, originality, relevance, significance, and validity.
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