哺乳动物接触微（纳米）塑料（MNPs）的发育毒性：综述。

IF 4.1 3区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES Toxics Pub Date : 2025-03-19 DOI:10.3390/toxics13030224

Gongxiang Xia, Teng Wan, Zhuan Chen, Cuiqing Liu, Ran Li

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引用次数: 0

摘要

微（纳米）塑料对生态环境和人类健康构成重大威胁。这篇综述系统地研究了哺乳动物中MNPs的发育毒性，特别关注了母体和父亲接触MNPs对后代的影响。有证据表明，MNPs可以穿过胎盘屏障，诱导胚胎、胎儿和胎盘的异常发育。这种破坏会导致后代出现一系列不良后果，包括神经发育异常、行为障碍、生殖系统损伤等。通过对现有文献的综合分析，本综述旨在为未来研究MNPs的发育毒性提供基础，并强调迫切需要采取行动减轻MNPs对人类健康和生态系统完整性的有害影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Developmental Toxicity of Micro(Nano)Plastics (MNPs) Exposure in Mammals: A Mini-Review.

Micro(nano)plastics (MNPs) pose a significant threat to both ecological environments and human health. This review systematically examines the developmental toxicity of MNPs in mammals, with a particular focus on the impact of maternal and paternal exposure on offspring. Evidence indicates that MNPs can cross placental barriers, inducing abnormal development of embryos, fetuses, and placentas. This disruption leads to a range of adverse outcomes, including neurodevelopmental abnormalities, behavioral disorders, reproductive system damage, etc., in offspring. Through a comprehensive analysis of the existing literature, this review aims to provide a foundation for future research on the developmental toxicity of MNPs and highlight the urgent need for action to mitigate the detrimental effects of MNPs on human health and ecosystem integrity.

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来源期刊

Toxics Chemical Engineering-Chemical Health and Safety

CiteScore

4.50

自引率

10.90%

发文量

681

审稿时长

6 weeks

期刊介绍： Toxics (ISSN 2305-6304) is an international, peer-reviewed, open access journal which provides an advanced forum for studies related to all aspects of toxic chemicals and materials. It publishes reviews, regular research papers, and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in detail. There is, therefore, no restriction on the maximum length of the papers, although authors should write their papers in a clear and concise way. The full experimental details must be provided so that the results can be reproduced. Electronic files or software regarding the full details of calculations and experimental procedure can be deposited as supplementary material, if it is not possible to publish them along with the text.