用于色盲管理的PDMS隐形眼镜中的原位还原金纳米颗粒

IF 4.6 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY RSC Advances Pub Date : 2025-04-22 DOI:10.1039/D4RA08879D
M. Aravind, Haider Butt and Sajan Daniel George
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引用次数: 0

摘要

色觉缺陷或色盲,是一种个体难以区分某些颜色的眼部疾病。虽然目前还没有治愈这种疾病的方法,但各种可穿戴设备可以用来改善受影响者的颜色感知。最常用的可穿戴设备是滤色眼镜和镜片,它们可以滤掉有问题的波长。最常见的色觉缺陷是红绿色盲。本研究将金纳米颗粒原位还原到隐形眼镜材料上,形成用于治疗红绿色盲的等离子体隐形眼镜。等离子体粒子的吸收在533 nm左右达到峰值,过滤掉了特定波长,显著增强了色盲和色盲的颜色感知。该研究还提出了一种通过等离子体透镜成像的方法,然后进行色盲视觉模拟,以复制色盲个体的视觉。当与石原试验相结合时,这种方法被证明可以有效地改善使用等离子体隐形眼镜的颜色感知。这项研究提出了一种简便的方法来制造稳定的、亲水的等离子体隐形眼镜来治疗色盲。它还提供了一种独特的方式来模拟色彩过滤对色盲个体视觉的影响。
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In situ reduced gold nanoparticles in PDMS contact lenses for color blindness management†

Color vision deficiency, or color blindness, is an ocular condition in which individuals have difficulty distinguishing between certain colors. While there is currently no cure for this condition, various wearables can be used to improve the color perception of those affected. The most common wearables used are color-filtering glasses and lenses, which filter out the problematic wavelengths. The most prevalent form of color vision deficiency is red-green color blindness. In this study, gold nanoparticles were in situ reduced onto contact lens material, forming plasmonic contact lenses targeted for red-green color blindness management. The absorption of the plasmonic particles, which peaked at around 533 nm, filtered out specific wavelengths to significantly enhance the color perception of both deuteranopia and protanopia. The study also presented an approach of imaging through the plasmonic lenses, followed by color blindness vision simulation to replicate a colorblind individual's vision. When combined with the Ishihara test, this approach proved to effectively improve color perception with the use of plasmonic contact lenses. The study presents a facile method for creating stable, hydrophilic plasmonic contact lenses to manage color blindness. It also offers a unique way to simulate the impact of color filtering on the vision of individuals with color blindness.

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来源期刊
RSC Advances
RSC Advances chemical sciences-
CiteScore
7.50
自引率
2.60%
发文量
3116
审稿时长
1.6 months
期刊介绍: An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.
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