{"title":"[从培养的胚胎大鼠细胞中提取的低分子量DNA的特性]。","authors":"R Manso-Martinez, W Frank","doi":"10.1515/znb-1972-1215","DOIUrl":null,"url":null,"abstract":"Normal embryonic rat cells, which are synchronized in G1 phase of their cell cycle, by incubation in serum-free medium contain a DNA fraction with a sedimentation coefficient S20 between 11 and 12. This double-stranded DNA shows a significantly higher buoyant density in caesiumchloride than does the bulk of cellular DNA, and its replication is not restricted to a distinct part of the S period. The possible role of these DNA subunits in the replication mechanism is discussed","PeriodicalId":78857,"journal":{"name":"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie","volume":"27 12","pages":"1507-15"},"PeriodicalIF":0.0000,"publicationDate":"1972-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/znb-1972-1215","citationCount":"0","resultStr":"{\"title\":\"[Properties of a low-molecular weight DNA from embryonic rat cells in culture].\",\"authors\":\"R Manso-Martinez, W Frank\",\"doi\":\"10.1515/znb-1972-1215\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Normal embryonic rat cells, which are synchronized in G1 phase of their cell cycle, by incubation in serum-free medium contain a DNA fraction with a sedimentation coefficient S20 between 11 and 12. This double-stranded DNA shows a significantly higher buoyant density in caesiumchloride than does the bulk of cellular DNA, and its replication is not restricted to a distinct part of the S period. The possible role of these DNA subunits in the replication mechanism is discussed\",\"PeriodicalId\":78857,\"journal\":{\"name\":\"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie\",\"volume\":\"27 12\",\"pages\":\"1507-15\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1972-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1515/znb-1972-1215\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/znb-1972-1215\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/znb-1972-1215","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Properties of a low-molecular weight DNA from embryonic rat cells in culture].
Normal embryonic rat cells, which are synchronized in G1 phase of their cell cycle, by incubation in serum-free medium contain a DNA fraction with a sedimentation coefficient S20 between 11 and 12. This double-stranded DNA shows a significantly higher buoyant density in caesiumchloride than does the bulk of cellular DNA, and its replication is not restricted to a distinct part of the S period. The possible role of these DNA subunits in the replication mechanism is discussed
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