{"title":"黄素依赖性羰基活化的模型研究:黄酮类对苯二酚还原羰基化合物。","authors":"G Blankenhorn, S Ghisla, P Hemmerich","doi":"10.1515/znb-1972-0909","DOIUrl":null,"url":null,"abstract":"The reduction of aldehydes by flavohydroquinone to yield the corresponding alcohols and flavoquinone is reported and discussed in view of its relevance to the mechanism of flavin-dependent dehydrogenation and carbonyl activation. With formaldehyde and flavohydroquinone formation of a covalent 5- (HO - CH2) Flred⁻ intermediate species is observed. In a reverse reaction 5-methylflavoquinonium cation undergoes an internal redox reaction to yield flavohydroquinone and formaldehyde.","PeriodicalId":78857,"journal":{"name":"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie","volume":"27 9","pages":"1038-40"},"PeriodicalIF":0.0000,"publicationDate":"1972-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/znb-1972-0909","citationCount":"9","resultStr":"{\"title\":\"Model studies on flavin-dependent carbonyl-activation: reduction of carbonyl compounds by flavohydroquinone.\",\"authors\":\"G Blankenhorn, S Ghisla, P Hemmerich\",\"doi\":\"10.1515/znb-1972-0909\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The reduction of aldehydes by flavohydroquinone to yield the corresponding alcohols and flavoquinone is reported and discussed in view of its relevance to the mechanism of flavin-dependent dehydrogenation and carbonyl activation. With formaldehyde and flavohydroquinone formation of a covalent 5- (HO - CH2) Flred⁻ intermediate species is observed. In a reverse reaction 5-methylflavoquinonium cation undergoes an internal redox reaction to yield flavohydroquinone and formaldehyde.\",\"PeriodicalId\":78857,\"journal\":{\"name\":\"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie\",\"volume\":\"27 9\",\"pages\":\"1038-40\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1972-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1515/znb-1972-0909\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/znb-1972-0909\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/znb-1972-0909","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Model studies on flavin-dependent carbonyl-activation: reduction of carbonyl compounds by flavohydroquinone.
The reduction of aldehydes by flavohydroquinone to yield the corresponding alcohols and flavoquinone is reported and discussed in view of its relevance to the mechanism of flavin-dependent dehydrogenation and carbonyl activation. With formaldehyde and flavohydroquinone formation of a covalent 5- (HO - CH2) Flred⁻ intermediate species is observed. In a reverse reaction 5-methylflavoquinonium cation undergoes an internal redox reaction to yield flavohydroquinone and formaldehyde.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
