何杰金氏病的皮肤定位。4例病例描述及文献复习]。

P Lucas, W V Bogomeletz, A Cattan
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引用次数: 0

摘要

皮肤受累在何杰金氏病中并不常见。在167例霍奇金患者中,我们观察到4例皮肤病变。临床和组织病理学特征进行了讨论,并与那些40其他文献中报道的充分记录的病例进行了比较。广泛的临床模式和变异性的结果强调。皮肤活检是强制性的,并提供诊断的主要证据;然而,里德·斯滕伯格细胞并不是绝对特异的,在确认一种需要主要治疗的疾病时必须谨慎。在大多数观察中,皮肤受累显然与预后无关。我们认为,具体何杰金氏皮肤病变的现实存在很大的保留。
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[Cutaneous localization of Hodgkin's disease. Description of 4 cases and review of the literature].

Cutaneous involvement is uncommon in Hodgkin disease. Among 167 Hodgkin patients, we observed skin lesions in four. Clinical and histopathological features are discussed and compared with those of 40 other well-documented cases previously reported in the literature. The wide spectrum of clinical patterns and variability of outcome are underlined. Skin biopsy is mandatory and provides cardinal evidence for diagnosis; however, the Reed Sternberg cell is not absolutely specific and caution must be taken in affirming a disease which implies major therapy. In most observations, skin involvement obviously has no bearing on prognosis. We believe that the reality of specific Hodgkin skin lesions is subject to major reservations.

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