癌前仓鼠颊袋DNA合成的日变化。

Cell and tissue kinetics Pub Date : 1983-11-01

L M Lin, R A Goepp

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引用次数: 0

摘要

各组小鼠右颊袋涂DMBA，每周2次，连续4、7周。结果发现，dba处理的仓鼠颊袋上皮细胞DNA合成和有丝分裂事件具有昼夜节律性和非随机分布。这些变化的程度明显大于未处理对照袋的变化。这一发现被描述为“共生现象”，即组织生长过程中具有同步DNA周期的基底细胞的非随机分组。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Diurnal variation of DNA synthesis in premalignant hamster cheek pouch.

The right cheek pouch of hamsters was painted twice a week with DMBA for 4 and 7 weeks in different groups. It was found that there were diurnal rhythms and non-random distributions of DNA synthesis and mitotic events in DMBA-treated hamster-cheek-pouch epithelium. The degree of these changes was markedly greater than the changes in non-treated control pouches. The finding of cluster formation was described as 'symphokinesis', the non-random grouping of basal cells with synchronous DNA cycles during tissue growth.

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来源期刊

Cell and tissue kinetics

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