胸腺对前体T细胞的影响。

Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-09-01

G Kraal, D Boden

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引用次数: 0

摘要

研究了胸腺对其骨髓前体的影响:用去胸腺供者的骨髓重建辐照小鼠，研究了T细胞分化。在注射后12个月，受体中前体的流入和向T细胞的分化没有改变。cfu对去胸腺动物的骨髓和脾脏的测定没有显示出数量的变化，但随着年龄的增长，在去胸腺动物和对照供体中观察到E/G比的变化。

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The influence of the thymus on precursor T cells.

The influence of the thymus on its bone marrow precursors was investigated: T cell differentiation was studied in irradiated mice reconstituted with bone marrow from thymectomized donors. Up to twelve months after TX the influx of precursors and differentiation into T cells were not changed in the recipients. CFU-s determination of bone marrow and spleen from thymectomized animals did not show a change in numbers but during ageing a shift of the E/G ratio was observed in thymectomized as well as control donors.

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Biomedicine / [publiee pour l'A.A.I.C.I.G.]

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