非洲爪蟾发育过程中的DNA甲基化酶

R.L.P. Adams, R.H. Burdon, S. Gibb, E.L. McKay
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引用次数: 7

摘要

非洲爪蟾胚胎和培养细胞中的DNA甲基化酶活性与哺乳动物组织中的DNA甲基化酶相似。在成熟的胚芽囊泡中发现很少或没有活性,尽管受精后核活性迅速上升。这种上升可能部分是由于细胞质酶的重新定位。
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DNA methylase during Xenopus laevis development

The DNA methylase activity present in embryos and cultured cells of Xenopus laevis resembles DNA methylase from mammalian tissues. Little or no activity is found in mature germinal vesicles, though nuclear activity rises rapidly after fertilization. This rise may result in part from a relocation of cytoplasmic enzyme.

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