【早期胃癌:大规模胃癌筛查项目的主要目标】。

G.E.N Pub Date : 1994-07-01
W Oliver
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摘要

在委内瑞拉Táchira国家,胃癌的发病率很高。早期胃癌(EGC)筛查始于1981年。它借鉴了日本的模式,将间接放射学(IR)推广到各个城市,提供筛选试验。有IR异常的受试者接受内窥镜检查。内窥镜检查发现病变,行活检。可治疗的病人去做手术;手术标本的诊断由训练有素的病理学家完成。积极跟进小儿麻痹症病例。从1981年到1992年,我们做了150.023次放射学检查,52562次胃内窥镜检查和18480次胃内窥镜活检。我们诊断了612例cg:450例晚期,102例术后确诊的113例EGCs;60例经影像学及内窥镜检查怀疑为EGCs,但因未行手术而未确诊。89例患者行胃切除术,13例行内镜切除。EGCs降低(IIc型,III型)占49%,升高(I型,IIa型)占26%,持平(IIb型)占6%,中间(IIa + IIc型)占19%。60%局限于粘膜,40%局限于粘膜下层。经组织病理学检查,60%已分化,40%未分化。在9%的病例中,我们发现淋巴结转移,只有2%的病例发现粘膜转移。EGC患者5年后生存率为93%。我们认为二级预防可以在高危地区通过适当的EGC筛查来完成。
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[Early gastric cancer: main objective in a mass screening program for gastric cancer].

In Táchira's State, Venezuela, there is a high incidence of Gastric Cancer. Screening for early gastric cancer (EGC) detection began in 1981. It observes the Japanese model, with Indirect Radiological (IR) as the move to the various Municipalities, offering the screening test. Subjects with IR abnormalities receive an invitation for an endoscopic examination. If lesions at endoscopy, biopsies were taken. Treatable patients went to surgery; the diagnosis on the surgical specimen was fulfilled by trained Pathologists. CGs cases are actively followed up. From 1981 to 1992 we did 150.023 radiological studies 52.562 gastric endoscopies and 18,480 endoscopic biopsies. We diagnosed 612 CGs:450 were advanced: 102 patients with 113 EGCs with confirmation after surgery; 60 cases were suspected by radiology and endoscopy as EGCs but were nor confirmed because the patients were not operated. 89 patients underwent gastroectomies, and 13 endoscopy resections. The EGCs were depressed (Types IIc, III) in 49% elevated (Types I, IIa) 26%, flat (Type IIb) 6% and intermediate (Types IIa + IIc) 19%. The invasion was confined to the mucosa in 60% and to the submucosa in 40%. By histopathology 60% were differentiated and 40% undifferentiated. In 9% we found metastasis in lymph nodes, only in 2% of the mucosal ones. Survival of patients with EGC after 5 year was 93%. We think a secondary prevention can be done in high risk regions through an appropriate screening for EGC.

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